Recombinant Human CNTF cell lysate
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Cat.No. : | CNTF-376HCL Optional Service: Optional requirements on this protein |
Description : | The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. |
Species : | Human |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name : | CNTF ciliary neurotrophic factor [ Homo sapiens ] |
Official Symbol : | CNTF |
Synonyms : | CNTF; ciliary neurotrophic factor; HCNTF; |
Gene ID : | 1270 |
mRNA Refseq : | NM_000614 |
Protein Refseq : | NP_000605 |
MIM : | 118945 |
UniProt ID : | P26441 |
Chromosome Location : | 11q12 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; |
Function : | ciliary neurotrophic factor receptor binding; cytokine activity; growth factor activity; interleukin-6 receptor binding; |
◆ Recombinant Protein
CNTF-1606H | Recombinant Human CNTF Protein, GST-tagged | +Inquiry |
Cntf-44M | Recombinant Active Mouse CNTF Protein, His-tagged(C-ter) | +Inquiry |
CNTF-43H | Recombinant Active Human CNTF Protein, His-tagged(C-ter) | +Inquiry |
CNTF-2013H | Recombinant Human CNTF Protein, His-tagged | +Inquiry |
Cntf-913M | Recombinant Mouse Cntf Protein, MYC/DDK-tagged | +Inquiry |
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◆ Native Protein
CNTF-26839TH | Native Human CNTF | +Inquiry |
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