cntf
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  • Official Full Name
  • ciliary neurotrophic factor
  • Background
  • Ciliary neurotrophic factor (CNTF); is a cytokine1 that supports survival and/or differentiation of a variety of neuronal cell types including sensory, sympathetic, and motoneurons.2 With these abilities, CNTF has implications for Parkinson's disease and
  • Synonyms
  • CNTF; ciliary neurotrophic factor; HCNTF
Cat.#:CNTF-2013HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CNTF Protein, His-tagged
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Cat.#:CNTF-1606HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CNTF Protein, GST-tagged
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Cat.#:CNTF-02HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Ciliary Neurotrophic Factor
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Cat.#:CNTF-06HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CNTF protein, MYC/DDK-tagged
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Cat.#:CNTF-11409HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CNTF, GST-tagged
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Cat.#:CNTF-161HTag:His/S
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CNTF protein, His/S-tagged
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Cat.#:CNTF-249HTag:Strep II
Source (Host):HEK293Species:Human
Product nameRecombinant Human CNTF, StrepII-tagged
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Cat.#:CNTF-26841THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CNTF
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Cat.#:CNTF-26842THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CNTF, His-tagged
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Cat.#:CNTF-36HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CNTF protein
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Cat.#:CNTF-566HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CNTF, His tagged
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Cat.#:Cntf-160MTag:His/S
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cntf protein, His/S-tagged
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Cat.#:CNTF-3682MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CNTF Protein
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Cat.#:Cntf-490MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cntf, His-tagged
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Cat.#:Cntf-565MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cntf
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Cat.#:CNTF-995MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse CNTF Protein, His-tagged
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Cat.#:CNTF-1500RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CNTF Protein
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Cat.#:Cntf-159RTag:His/S
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Cntf protein, His/S-tagged
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Cat.#:Cntf-296RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ciliary Neurotrophic Factor
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Cat.#:Cntf-374RTag:His
Source (Host):E.coliSpecies:Rat
Product nameRecombinant Rat Cntf Protein, His-tagged
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Cat.#:Cntf-579RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Cntf, None tagged
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Cat.#:Cntf-594RTag:
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Cntf
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Cat.#:CNTF-588RTag:His/T7
Source (Host):E. coliSpecies:Rabbit
Product nameRecombinant Rabbit CNTF protein, His & T7-tagged
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Cat.#:CNTF-7041CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CNTF
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Cat.#:CNTF-7368ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CNTF
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Cat.#:CNTF-587PTag:His/T7
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig CNTF protein, His & T7-tagged
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Cat.#:CNTF-08HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Ciliary Neurotrophic Factor, His-tagged
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Cat.#:CNTF-26839THTag:
Source (Host):E. coliSpecies:Human
Product nameNative Human CNTF
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Cat.#:CNTF-376HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CNTF cell lysate
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Cat.#:CNTF-139HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Ciliary Neurotrophic Factor (rDNA derived) Reference standard
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Involved Pathway

CNTF involved in several pathways and played different roles in them. We selected most pathways CNTF participated on our site, such as Cytokine-cytokine receptor interaction, Delta-Notch Signaling Pathway, Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CNTF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
CD70; LIFRA; HGF; TNFB; CCL1; CCL21B; Cxcl15; ACVR2AA; FLT4; IL23R
Delta-Notch Signaling Pathway
SMAD3B; CNTFR; ASCL1; ADAM10A; TUBB3; WDR12; RING1; HES6; HEY2; CNTF
Jak-STAT signaling pathway
STAT2; JAK2B; IL7; SOCS3B; IL15RA; IFNA5; CRFB4; CCND2; GHRA; IL29

Protein Function

CNTF has several biochemical functions, for example, ciliary neurotrophic factor receptor binding, growth factor activity, interleukin-6 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CNTF itself. We selected most functions CNTF had, and list some proteins which have the same functions with CNTF. You can find most of the proteins on our site.
Function
Related Protein
Function ciliary neurotrophic factor receptor binding
Related Protein CNTF; IL6ST; LIFR; CLCF1; Ctf2
Function growth factor activity
Related Protein FGF13A; GFER; IL9; NRG4; FGF8B; BMP10; NRG1; MDK; VEGFB; GDF10B
Function interleukin-6 receptor binding
Related Protein IL6; ERAP1; CNTF; ADAM17; PYCARD
Function protein binding
Related Protein PTK6; CDH23; CSTF3; CLASP1; LRP4; AP1M1; CTNNB1; FANCF; PRR3; CCNT1

Interacting Protein

CNTF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CNTF here. Most of them are supplied by our site. Hope this information will be useful for your research of CNTF.
TRIP6; KRT40; IL6ST; LIFR; STK16; VHL; EIF3E; ICA1; EXT1; EXT2

CNTF Related Gene Family

IL