"FGF10" Related Products

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Recombinant Human FGF10

Cat.No.: FGF10-26205TH
Product Overview: Recombinant full length human FGF10,is a single, non-glycosylated polypeptide chain containing 170 amino acids, 19 kDa.
Description: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.
Source: E. coli
Biological activity: Specific activity of 2 x 106 Units/mg.
Form: Lyophilised:Reconstitute in sterile 18MOhm/cm water to not less than 100μg/ml, which can then be further diluted to other aqueous solutions.
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 80mM Sodium chloride, 5mM Sodium phosphate, pH 7.4
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: The sequence of the first five N-terminal amino acids was determined and was found to be Met-Leu-Glu-Gln-Asp.
Sequence Similarities: Belongs to the heparin-binding growth factors family.
Gene Name: FGF10 fibroblast growth factor 10 [ Homo sapiens ]
Official Symbol: FGF10
Synonyms: FGF10; fibroblast growth factor 10;
Gene ID: 2255
mRNA Refseq: NM_004465
Protein Refseq: NP_004456
MIM: 602115
Uniprot ID: O15520
Chromosome Location: 5p13-p12
Pathway: Developmental Biology, organism-specific biosystem; Downstream signaling of activated FGFR, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR1 ligand binding and activation, organism-specific biosystem; FGFR1b ligand binding and activation, organism-specific biosystem;
Function: chemoattractant activity; fibroblast growth factor receptor binding; growth factor activity; heparin binding; type 2 fibroblast growth factor receptor binding;

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