Recombinant Human Human Human Human ADRB2

• Cat.No.: GNB1-31359TH
• Product Overview: Recombinant full length Human beta 2 Adrenergic Receptor with N terminal FLAG tag fused to Gia3 via a His tag, co-expressed in Sf9 insect cells with G?12 subunits,predicted molecular weight of the fusion protein is 36 kDa.

Specification

• Description: Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene uses alternative polyadenylation signals.
• Conjugation: FLAG,His
• Biological activity: Receptor expression level: 5.4 pmol/mg.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.

Gene Information

• Gene Name: GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 [ Homo sapiens ]
• Official Symbol: GNB1
• Synonyms: GNB1; guanine nucleotide binding protein (G protein), beta polypeptide 1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
• Gene ID: 2782
• mRNA Refseq: NM_002074
• Protein Refseq: NP_002065
• MIM: 139380
• Uniprot ID: P62873
• Chromosome Location: 1p36.33
• Pathway: ADP signalling through P2Y purinoceptor 1, organism-specific biosystem; ADP signalling through P2Y purinoceptor 12, organism-specific biosystem; Activation of G protein gated Potassium channels, organism-specific biosystem; Activation of GABAB receptors, organism-specific biosystem; Activation of Kainate Receptors upon glutamate binding, organism-specific biosystem
• Function: G-protein coupled receptor binding; GTPase activity; GTPase binding; signal transducer activity; type 1 angiotensin receptor binding