Recombinant Human GUK1, His-tagged GUK1-29176TH

Recombinant Human GUK1, His-tagged

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Recombinant Human GUK1, His-tagged

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Cat.No. : GUK1-29176TH
Product Overview : Recombinant full length Human Guanylate kinase with N terminal His tag; 217 amino acids with tag, Predicted MWt 23.9kDa.
Description : The protein encoded by this gene is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene.
Protein length : 197 amino acids
Conjugation : HIS
Molecular Weight : 23.900kDa inclusive of tags
Source : E. coli
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHHSSGLV PRGSHMSGPRPVVLS GPSGAGKSTLLKRLL QEHSGIFGFSVSHTT RNPRPGEENGKDYYF VTREVMQRDIAAGDF IEHAEFSGNLYGTSK VAVQAVQAMNRICVL DVDLQGVRNIKATDL RPIYISVQPPSLHVL EQRLRQRNTETEESL VKRLAAAQADMESSK EPGLFDVVIINDSLD QAYAELKEALSEEIK KAQRTGA
Sequence Similarities : Belongs to the guanylate kinase family.Contains 1 guanylate kinase-like domain.
Gene Name : GUK1 guanylate kinase 1 [ Homo sapiens ]
Official Symbol : GUK1
Synonyms : GUK1; guanylate kinase 1; guanylate kinase;
Gene ID : 2987
mRNA Refseq : NM_000858
Protein Refseq : NP_000849
MIM : 139270
Uniprot ID : Q16774
Chromosome Location : 1q32-q41
Pathway : Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem;
Function : ATP binding; guanylate kinase activity; kinase activity; nucleotide binding; transferase activity;

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