Recombinant Human Intercellular Adhesion Molecule 3
Cat.No. : | ICAM3-1627H |
- Specification
- Gene Information
- Related Products
Cat. No. : | ICAM3-1627H |
Description : | Intercellular adhesion molecule 3 (ICAM3) also known as CD50 (Cluster of Differentiation 50) is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins that bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signaling molecule. ICAM-3 is potentially the most important ligand for LFA-1 in the initiation of the immune response because the expression of ICAM-1 on resting leukocytes is low.1 ICAM-3 is closely related to ICAM-1.ICAM-3 is essentially restricted to the haemopoietic system and is reciprocal in its expression to ICAM-1, in that it is present on resting cells and its level falls as a result of cell activation. |
Source : | Mammalian cells |
State Of Matter : | Lyophilized. |
Purity : | >95% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Molecular Weight : | The predicted molecular weight of Recombinant Human ICAM-3 is Mr 76.7 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 120 kDa. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
Gene Name : | ICAM3 intercellular adhesion molecule 3 [ Homo sapiens ] |
Synonyms : | ICAM3; intercellular adhesion molecule 3; CD50; CDW50; ICAM-R; CDw50; intercellular adhesion molecule-3; Intercellular adhesion molecule 3; ICAM-3; CD50 antigen |
Gene ID : | 3385 |
mRNA Refseq : | NM_002162 |
Protein Refseq : | NP_002153 |
MIM : | 146631 |
UniProt ID : | P32942 |
Chromosome Location : | 19p13.3-p13.2 |
Pathway : | Cell adhesion molecules (CAMs); Integrin cell surface interactions; Signaling in Immune system |
Function : | integrin binding |
Products Types
◆ Recombinant Protein | ||
ICAM3-001H | Recombinant Human ICAM3 Protein, GST-tagged | +Inquiry |
ICAM3-4421H | Recombinant Human ICAM3 Protein, His (Fc)-Avi-tagged | +Inquiry |
ICAM3-060H | Recombinant Human ICAM3 Protein, C-His-tagged | +Inquiry |
ICAM3-796H | Recombinant Human ICAM3 Protein, MYC/DDK-tagged | +Inquiry |
ICAM3-2007R | Recombinant Rhesus Macaque ICAM3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ICAM3-2417HCL | Recombinant Human ICAM3 cell lysate | +Inquiry |
ICAM3-2935HCL | Recombinant Human ICAM3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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