Recombinant Human IRAK2

• Cat.No.: IRAK2-27503TH
• Product Overview: Recombinant full length Human IRAK2 with N-terminal proprietary tag; MWt 103kDa.

Specification

• Description: IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.
• Protein length: 625 amino acids
• Molecular Weight: 103.000kDa inclusive of tags
• Source: Baculovirus
• Biological activity: The specific activity of IRAK2-27503TH was determined to be 6 nmol/min/mg.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.

Gene Information

• Gene Name: IRAK2 interleukin-1 receptor-associated kinase 2 [ Homo sapiens ]
• Official Symbol: IRAK2
• Synonyms: IRAK2; interleukin-1 receptor-associated kinase 2; interleukin-1 receptor-associated kinase-like 2
• Gene ID: 3656
• mRNA Refseq: NM_001570
• Protein Refseq: NP_001561
• MIM: 603304
• Uniprot ID: O43187
• Chromosome Location: 3p25.2
• Pathway: Activated TLR4 signalling, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; IL-1 Signaling Pathway, organism-specific biosystem
• Function: ATP binding; NF-kappaB-inducing kinase activity; nucleotide binding; protein binding; protein heterodimerization activity