|Cat. No. :
|Product Overview :
||Recombinant Human VEGFR2 encoding amino acid residues 1 - 764 of the extracellular domain of human VEGFR2 was fused to a 6X His-tagged Fc of human IgG1 via the peptide (IEGRMD). It was expressed inNSO Cells.
||Vascular endothelial growth factor receptor 2 (VEGF R2) is a transmembrane glycoprotein that is a member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration, and differentiation.
|State Of Matter :
||>90% by SDS Page and analyzed by silver stain.
||<1.0 EU/µg as determined by the LAL method.
|Molecular Weight :
||The predicted molecular weight of Recombinant Human KDR is Mr 110 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 160-170 kDa.
|Biological Activity :
||The biological activity of Human KDR was determined by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells. The expected ED50 for this effect is typically 4-8 ng/ml in the presence of 5 ng/ml recombinant human VEGF165.
|Storage And Stability :
||This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.