"PFDN5" Related Products


Recombinant Human PFDN5, His-tagged

Cat.No.: PFDN5-29723TH
Product Overview: Recombinant full length protein, corresponding to amino acids 1-154 of Human PFDN5 with N terminal His tag, 21kDa.
Description: This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described.
Conjugation: HIS
Source: E. coli
Tissue specificity: Highly expressed in pancreas and skeletal muscle and moderately in other tissues.
Form: Lyophilised:Reconstitute with 77 μl aqua dest.
Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the prefoldin subunit alpha family.
Gene Name: PFDN5 prefoldin subunit 5 [ Homo sapiens ]
Official Symbol: PFDN5
Synonyms: PFDN5; prefoldin subunit 5; prefoldin 5; MM 1; PFD5;
Gene ID: 5204
mRNA Refseq: NM_002624
Protein Refseq: NP_002615
MIM: 604899
Uniprot ID: Q99471
Chromosome Location: 12q13.13
Pathway: Chaperonin-mediated protein folding, organism-specific biosystem; Cooperation of Prefoldin and TriC/CCTin actin and tubulin folding, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Prefoldin mediated transfer of substrateto CCT/TriC, organism-specific biosystem; Protein folding, organism-specific biosystem;
Function: protein binding; transcription corepressor activity; unfolded protein binding;

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