Recombinant Mouse Insulin-like Growth Factor Binding Protein 3
Cat.No. : | Igfbp3-1750M |
Product Overview : | Recombinant Mouse Igfbp3 was fused to the human CD33 signal peptide. This chimeric protein was expressed inNSO cells. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Igfbp3-1750M |
Description : | Insulin-like growth factor binding protein 3, also known as IGFBP3, is a member of the insulin-like growth factor binding protein (IGFBP) family that are cysteine-rich proteins that act as a carrier protein. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. |
Molecular Weight : | The predicted molecular weight of Recombinant Mouse IGFBP-3 is Mr 29;.4 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 40-50 kDa. |
Source : | Mammalian cells |
State Of Matter : | Lyophilized. |
Purity : | >95% by SDS Page and analyzed by silver stain. |
Formulation : | This recombinant protein was lyophilized from a 0.2 μm filtered solution in 35% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA). |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Biological Activity : | The biological activity of Mouse IGFBP-3 was determined by its ability to inhibit the biological activity of rmIGF-II on MCF-7 cells (Karey, K.P. et al., 1988, Cancer Research 48:4083). The expected ED50 for this effect is typically 0.125 - 0.5 μg/ml in the presence of 30 ng/ml rmIGF-II. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | Igfbp3 insulin-like growth factor binding protein 3 [ Mus musculus ] |
Synonyms : | Igfbp3; insulin-like growth factor binding protein 3; IGFBP-3; IGgfbp3; AI649005; OTTMUSP00000005343 |
Gene ID : | 16009 |
mRNA Refseq : | NM_008343 |
Protein Refseq : | NP_032369 |
UniProt ID : | P47878 |
Chromosome Location : | 11 A1; 11 1.35 cM |
Pathway : | p53 signaling pathway |
Function : | growth factor binding; insulin-like growth factor binding |
Products Types
◆ Recombinant Protein | ||
IGFBP3-4353H | Recombinant Human IGFBP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
IGFBP3-2678H | Recombinant Human IGFBP3 protein(121-200 aa), C-His-tagged | +Inquiry |
Igfbp3-1655M | Recombinant Mouse Igfbp3 Protein, His-tagged | +Inquiry |
Igfbp3-10570M | Recombinant Mouse Igfbp3 Protein, His (Fc)-Avi-tagged | +Inquiry |
IGFBP3-2039R | Recombinant Rhesus Macaque IGFBP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IGFBP3-1230CCL | Recombinant Cynomolgus IGFBP3 cell lysate | +Inquiry |
IGFBP3-2927HCL | Recombinant Human IGFBP3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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