Recombinant Human SYK
Cat.No. : | SYK-31488TH |
Product Overview : | Recombinant full length Syk protein (Human), was expressed by baculovirus in Sf9 insect cells using an N-terminal tag, MW 100 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.Contains 1 protein kinase domain.Contains 2 SH2 domains. |
Gene Name : | SYK spleen tyrosine kinase [ Homo sapiens ] |
Official Symbol : | SYK |
Synonyms : | SYK; spleen tyrosine kinase; tyrosine-protein kinase SYK; |
Gene ID : | 6850 |
mRNA Refseq : | NM_001135052 |
Protein Refseq : | NP_001128524 |
MIM : | 600085 |
Uniprot ID : | P43405 |
Chromosome Location : | 9q22 |
Pathway : | Alpha-synuclein signaling, organism-specific biosystem; Atypical NF-kappaB pathway, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; |
Function : | ATP binding; integrin binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
SYK-030H | Recombinant Human SYK Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
SYK-0754H | Recombinant Human SYK Protein (E356-N635), Tag Free | +Inquiry |
SYK-5518R | Recombinant Rat SYK Protein, His (Fc)-Avi-tagged | +Inquiry |
SYK-109H | Recombinant Human SYK Protein, His-FLAG-tagged | +Inquiry |
SYK-0753H | Recombinant Human SYK Protein (E356-N635), His tagged | +Inquiry |
◆ Lysates | ||
SYK-1320HCL | Recombinant Human SYK 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1625 | SYK Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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