Recombinant Human C-src Tyrosine Kinase, GST-tagged, Active
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Cat. No. : | CSK-288H |
Product Overview : | Recombinant full-length human CSK was expressed by baculovirus inSf9 insect cellsusing a N-terminal GST tag. MW= 78 kDa. |
Description : | CSK is a cytoplasmic tyrosine kinase that has been shown to downregulate the tyrosine kinase activity of the c-src through tyrosine phosphorylation of the c-src carboxy terminus. A yeast 2-hybrid system has been used to identify proteins associated with CSK. The Src homology-3 (SH3) domain of CSK associates with a proline-rich region of PEP, a protein-tyrosine phosphatase expressed in hemopoietic cells. |
Source : | Sf9 insect cellsusing baculovirus. |
Sequence : | Full-lengt h. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | CSK c-src tyrosine kinase [ Homo sapiens ] |
Synonyms : | CSK; c-src tyrosine kinase; MGC117393; EC 2.7.10.2 |
Gene ID : | 1445 |
mRNA Refseq : | NM_001127190 |
Protein Refseq : | NP_001120662 |
MIM : | 124095 |
UniProt ID : | P41240 |
Chromosome Location : | 15q23-q25 |
Pathway : | Chemokine signaling pathway; Epithelial cell signaling in Helicobacter pylori infection; Neurotrophin signaling pathway; Regulation of actin cytoskeleton; Integrin cell surface interactions; Signaling in Immune system; Signaling by EGFR |
Function : | ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein C-terminus binding; transferase activity |
◆ Recombinant Protein
CSK-576H | Recombinant Human CSK Protein, His-tagged | +Inquiry |
CSK-342H | Recombinant Human CSK Protein, GST-tagged | +Inquiry |
Csk-942M | Recombinant Mouse Csk Protein, MYC/DDK-tagged | +Inquiry |
CSK-1979H | Recombinant Human CSK Protein, GST-tagged | +Inquiry |
CSK-3345H | Recombinant Human CSK Protein, MYC/DDK-tagged | +Inquiry |
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◆ Native Protein
CSK-27872TH | Native Human CSK | +Inquiry |
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◆ Lysates
CSK-628HCL | Recombinant Human CSK cell lysate | +Inquiry |
CSK-001MCL | Recombinant Mouse CSK cell lysate | +Inquiry |
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