Recombinant Human Nei Endonuclease VIII-like 2 (E. coli)
Cat.No. : | NEIL2-586H |
Product Overview : | Recombinant human NEIL2 was expressed in and purified fromE. coli. |
- Specification
- Gene Information
- Related Products
Cat. No. : | NEIL2-586H |
Description : | NEIL2 is a DNA glycosylase involved in base excision repair of oxidative DNA damage. It is a member of the Fpg/Nei/NEIL family of bi-functional DNA glycosylases. Following its glycosylase action, NEIL2 catalyzes sequential β-elimination and δ-elimination reactions via its associated AP lyase. This results in a one-nucleotide gap in DNA containing a 3' phosphate group. A phosphatase is needed to remove the 3'phosphate group before DNA repair synthesis can occur. |
Source : | E. coli. |
Purity : | Apparent homogeneity by SDS-PAGE and Coomassie blue staining. |
Formulation : | 20 mM Tris-HCl, pH 7.5, 300 mM NaCl, 10% glycerol. |
Storage : | Store at -70°C. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | NEIL2 nei endonuclease VIII-like 2 (E. coli) [ Homo sapiens ] |
Synonyms : | NEIL2; nei endonuclease VIII-like 2 (E. coli); NEH2; NEI2; MGC2832; MGC4505; FLJ31644; nei like 2; EC 4.2.99.18; DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; Nei-like protein 2; Nei homolog 2; Nei-like 2 |
Gene ID : | 252969 |
mRNA Refseq : | NM_001135746 |
Protein Refseq : | NP_001129218 |
MIM : | 608933 |
UniProt ID : | Q969S2 |
Chromosome Location : | 8p23.1 |
Pathway : | Base excision repair |
Function : | DNA-(apurinic or apyrimidinic site) lyase activity; damaged DNA binding; hydrolase activity, hydrolyzing N-glycosyl compounds; lyase activity; metal ion binding; microtubule binding; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
Neil2-4366M | Recombinant Mouse Neil2 Protein, Myc/DDK-tagged | +Inquiry |
NEIL2-351H | Recombinant Human NEIL2 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
NEIL2-15866H | Recombinant Human NEIL2, His-tagged | +Inquiry |
NEIL2-5185C | Recombinant Chicken NEIL2 | +Inquiry |
NEIL2 -1542H | Recombinant Human NEIL2 protein | +Inquiry |
◆ Lysates | ||
NEIL2-3881HCL | Recombinant Human NEIL2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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