Recombinant Mouse Neil2 Protein, Myc/DDK-tagged
Cat.No. : | Neil2-4366M |
Product Overview : | Purified recombinant protein of mouse full-length nei like 2 (E. coli) (Neil2), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double-stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 36.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Neil2 nei like 2 (E. coli) [ Mus musculus (house mouse) ] |
Official Symbol : | Neil2 |
Synonyms : | NEIL2; nei like 2 (E. coli); endonuclease 8-like 2; nei homolog 2; nei-like protein 2; endonuclease VIII-like 2; DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; NEH2; Gm1212 |
Gene ID : | 382913 |
mRNA Refseq : | NM_201610 |
Protein Refseq : | NP_963904 |
UniProt ID : | Q6R2P8 |
Products Types
◆ Recombinant Protein | ||
NEIL2-351H | Recombinant Human NEIL2 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
NEIL2-5185C | Recombinant Chicken NEIL2 | +Inquiry |
NEIL2-3048H | Recombinant Human NEIL2 protein, His-tagged | +Inquiry |
NEIL2-2042H | Recombinant Human Nei Endonuclease VIII-like 2 (E. coli) | +Inquiry |
NEIL2-15866H | Recombinant Human NEIL2, His-tagged | +Inquiry |
◆ Lysates | ||
NEIL2-3881HCL | Recombinant Human NEIL2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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