Recombinant Mouse Il6ra, His tagged
Cat.No. : | Il6ra-2297M |
Product Overview : | Recombinant Mouse Il6ra (NP_034689.2) extracellular domain (Ile 44-Glu 357), fused with a C-terminal polyhistidine tag, was produced in Human Cell. |
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- Specification
- Gene Information
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Source : | HEK293 |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized from sterile 50 mM Tris, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : | The recombinant mouse IL6Rα comprises 349 amino acids with a predicted molecular mass of 39 kDa. As a result of glycosylation, it migrates as an approximately 55-60 kDa band in SDS-PAGE under reducing conditions. |
Protein Length : | Ile 44-Glu 357 |
Endotoxin : | < 1.0 EU per μg protein as determined by the LAL method. |
Purity : | > 97 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | Il6ra interleukin 6 receptor, alpha [ Mus musculus ] |
Official Symbol : | Il6ra |
Synonyms : | IL6RA; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; IL-6RA; IL-6R 1; IL-6R-alpha; IL-6R subunit alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; Il6r; CD126; IL-6R; MGC30256; |
Gene ID : | 16194 |
mRNA Refseq : | NM_010559 |
Protein Refseq : | NP_034689 |
Products Types
◆ Recombinant Protein | ||
IL6RA-4520M | Recombinant Mouse IL6RA Protein, His (Fc)-Avi-tagged | +Inquiry |
IL6RA-3322H | Active Recombinant Human IL6RA protein | +Inquiry |
IL6RA-3324H | Active Recombinant Human IL6RA protein | +Inquiry |
Il6ra-1246M | Recombinant Mouse Il6ra Protein, MYC/DDK-tagged | +Inquiry |
Il6ra-583M | Recombinant Mouse Il6ra protein, His-tagged | +Inquiry |
◆ Lysates | ||
IL6R-2590MCL | Recombinant Mouse IL6R cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionIl6ra blocks the binding of the interleukin-6 receptor by acting on it, thereby affecting its immunomodulatory effect and reducing inflammation.
The efficacy of Il6ra is related to the severity of the disease, disease type and individual differences of patients, and should be judged by professional physicians according to the situation.
Il6ra can be used to treat rheumatoid arthritis, psoriasis, alopecia areata and other autoimmune diseases.
Almost all treatments have some kind of side effect, but the occurrence of side effects can be reduced with proper dosing and monitoring.
Recombinant Il6ra inhibits the immune response by inhibiting the cytokine activity of interleukin-6.
In addition to the autoimmune diseases mentioned above, Il6ra may also be used in the future to treat chronic inflammatory bowel disease, neurodegenerative diseases, and cancer.
Customer Reviews (3)
Write a reviewIt has good effect and stability in gene expression regulation.
Will not interact with other drugs, will not affect.
The application performance is stable in common colorimetric reactions.
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