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Recombinant Human LGALS8, His-tagged

Cat.No. : LGALS8-2784H
Product Overview : Recombinant human LGALS8 protein (1-317aa), fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
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Cat. No. : LGALS8-2784H
Description : LGALS8, also known as prostate-specific membrane antigen (PCTA1), is an additional prostate-specific antigen that is overexpressed only in malignant tumors and therefore is a more specific identifier of malignancies. It is a member of the galectin gene family which mediates both cell-cell and cell matrix interactions in a manner similar to the selectin subgroup of C-type lectins.
Source : E.coli.
Sequences : MGSSHHHHHH SSGLVPRGSH MMLSLNNLQN IIYNPVIPFV GTIPDQLDPG TLIVIRGHVP SDADRFQVDL QNGSSMKPRA DVAFHFNPRF KRAGCIVCNT LINEKWGREE ITYDTPFKRE KSFEIVIMVL KDKFQVAVNG KHTLLYGHRI GPEKIDTLGI YGKVNIHSIG FSFSSDLQST QASSLELTEI SRENVPKSGT PQLRLPFAAR LNTPMGPGRT VVVKGEVNAN AKSFNVDLLA GKSKDIALHL NPRLNIKAFV RNSFLQESWG EEERNITSFP FSPGMYFEMI IYCDVREFKV AVNGVHSLEY KHRFKELSSI DTLEINGDIH LLEVRSW.
Form : Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M Nacl, 1mM DTT, 10% glycerol.
Molecular Weight : 37.9 kDa (337aa),confirmed by MALDI-TOF.
Purity : > 90% by SDS – PAGE.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : LGALS8 lectin, galactoside-binding, soluble, 8 [ Homo sapiens ]
Synonyms :
LGALS8; lectin, galactoside-binding, soluble, 8; OTTHUMP00000037957; OTTHUMP00000037958; OTTHUMP00000037960; Po66 carbohydrate binding protein; galectin 8; galectin-8; galectin-8g; po66 carbohydrate-binding protein; prostate carcinoma tumor antigen 1; Gal-8; PCTA1; PCTA-1; Po66-CBP
Gene ID : 3964
mRNA Refseq : NM_006499
Protein Refseq : NP_006490
MIM : 606099
UniProt ID : O00214
Chromosome Location : 1q43
Function : sugar binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What role does LGALS8 play in immune responses? 10/15/2022

LGALS8 is involved in immune system modulation, influencing immune cell activation and response.

How does LGALS8 interact with other proteins in cell signaling pathways? 08/28/2022

LGALS8 interacts with a range of proteins, participating in diverse signaling pathways and cellular functions.

How do genetic variations in LGALS8 affect cellular signaling? 08/02/2021

Genetic mutations in LGALS8 can lead to altered cell signaling, impacting various biological processes.

How does LGALS8 contribute to apoptosis regulation? 03/15/2021

It plays a role in apoptosis regulation, affecting cell survival and death mechanisms.

What is the impact of altered LGALS8 activity on cancer progression? 10/23/2020

Altered LGALS8 activity is associated with cancer development, influencing tumor cell survival and metastasis.

What potential therapeutic applications arise from targeting LGALS8 in disease treatment? 05/07/2018

Targeting LGALS8 offers potential for treating diseases, including cancer, by modulating key cellular processes.

What is the primary role of LGALS8 in cell communication? 04/03/2017

LGALS8, a galectin protein, is involved in modulating cell communication, particularly in cell-cell and cell-matrix interactions.

Customer Reviews (3)

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Reviews
08/28/2022

    Expertise shines, supports research progress.

    10/23/2020

      Top-notch analysis, highly recommended for research projects.

      05/07/2018

        Reliable data source, a research necessity.

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