Expand| Cat. No. : | UBA1-58H |
| Product Overview : | Recombinant Human Ubiquitin-like Modifier Activating Enzyme 1 was expressed inSf9 cells. |
| Description : | Ubiquitin Activating Enzyme (E1) is responsible for the first step in ubiquitin-protein isopeptide bond formation. E1 catalyzes the activation of the C-terminal carboxyl group of ubiquitin by forming a high-energy thioester bond in an ATP-dependent manner. |
| Source : | Sf9 cells. |
| Form : | Solution in 50 mM HEPES pH 8.0. |
| Storage : | −70°C. |
| Gene Name : | UBA1 ubiquitin-like modifier activating enzyme 1 [ Homo sapiens ] |
| Synonyms : | UBA1; ubiquitin-like modifier activating enzyme 1; A1S9; A1ST; GXP1; UBE1; A1S9T; AMCX1; SMAX2; UBA1A; UBE1X; MGC4781; UBA1, ubiquitin-activating enzyme E1 homolog A; A1S9T and BN75 temperature sensitivity complementing; ubiquitin-activating enzyme E1; EC 6.3.2.19 |
| Gene ID : | 7317 |
| mRNA Refseq : | NM_003334 |
| Protein Refseq : | NP_003325 |
| MIM : | 314370 |
| UniProt ID : | P22314 |
| Chromosome Location : | Xp11.23 |
| Pathway : | Parkinson"s disease; Ubiquitin mediated proteolysis |
| Function : | ATP binding; ligase activity; nucleotide binding; small protein activating enzyme activity; protein binding |
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