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| Cat.No.: | NRG1-139HG |
| Product Overview: | Recombinant Human NRG1, Thr176-Lys246, was produced in E. coli using non-animal reagents in an animal-free facility under cGMP guidelines. |
| Source: | E. coli |
| Species: | Human |
| Form: | Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA. |
| Bio-activity: | Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083. |
| Molecular Mass: | Predicted Molecular Mass: 8 kDa SDS-PAGE: 8 kDa, reducing conditions |
| N-terminal Sequence Analysis: | Thr-Ser-His-Leu-Val-Lys-(Cys)-Ala-Glu-Lys |
| Endotoxin: | <0.01 EU per 1 μg of the protein by the LAL method. |
| Purity: | >97%, by SDS-PAGE with silver staining, under reducing conditions. |
| Storage: | Avoid repeated freeze-thaw cycles. 12 months, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
| Reconstitution: | Reconstitute at 100 μg/mL in PBS. |
| Quality Statement: | Our GMP proteins are produced according to relevant sections of the following documents: WHO TRS, No. 822, 1992 Annex 1, Good Manufacturing Practices for Biological Products; USP Chapter 1043, Ancillary Materials for Cell, Gene and Tissue-Engineered Products and USP Chapter 92, Growth Factors and Cytokines Used in Cell Therapy Manufacturing. |
| Shipping: | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
| Gene Name: | NRG1 neuregulin 1 [ Homo sapiens ] |
| Official Symbol: | NRG1 |
| Synonyms: | NRG1; neuregulin 1; HGL; pro-neuregulin-1, membrane-bound isoform; GGF; HRG; NDF; MSTP131; pro-NRG1; glial growth factor; neu differentiation factor; GGF2; HRG1; HRGA; SMDF; MST131; |
| Gene ID: | 3084 |
| mRNA Refseq: | NM_001159995 |
| Protein Refseq: | NP_001153467 |
| MIM: | 142445 |
| UniProt ID: | Q02297 |
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