Human Alpha-Fetoprotein

• Cat.No.: AFP-4769H
• Product Overview: This antigen is ideal for labeling or immunization purposes.

Specification

• Cat. No.: AFP-4769H
• Description: Alpha-fetoprotein (AFP, α-fetoprotein; also sometimes called alpha-1-fetoprotein or alpha-fetoglobulin) is a protein that in humans is encoded by the AFP gene. AFP is a major plasma protein produced by the yolk sac and the liver during fetal development that is thought to be the fetal form of serum albumin. The AFP gene is located on the q arm of chromosome 4 (4q25). AFP binds to copper, nickel, fatty acids and bilirubin and is found in monomeric, dimeric and trimeric forms.
• Source: Human cord serum
• Species: Human
• Form: Liquid. The antigen is in 0.1M Sodium Phosphate buffer, 0.2M NaCl, pH 7.4, with 0.1% sodium azide as preservative.
• Contaminants: None detected by reduced and non-reduced SDS-PAGE.
• Purity: >98% By SDS PAGE
• Concentration: 2.3 mg/ml
• Biohazard: Raw material tested at the donor level by approved FDA methods and found to be negative for anti-HCV, anti-HIV-1 and 2, and HBsAg.
• Storage: Store between 2-8°C. for short term. For long-term storage, aliquot and freeze at -20°C.

Gene Information

• Gene Name: AFP alpha-fetoprotein [ Homo sapiens ]
• Official Symbol: AFP
• Synonyms: AFP; alpha-fetoprotein; FETA; HPAFP; OTTHUMP00000160480; OTTHUMP00000220440; alpha-fetoglobulin; alpha-1-fetoprotein
• Gene ID: 174
• mRNA Refseq: NM_001134
• Protein Refseq: NP_001125
• MIM: 104150
• UniProt ID: P02771
• Chromosome Location: 4q11-q13
• Pathway: Direct p53 effectors; FOXA2 and FOXA3 transcription factor networks; Glucocorticoid receptor regulatory network
• Function: metal ion binding