Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Native Human AFP Protein

Cat.No. : AFP-412H
Product Overview : Human AFP native protein from human urine, Iodination Grade.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
Source : Human
Species : Human
Form : Liquid
Purity : >= 98% by SDS-PAGE
Applications : Antibody Production
SDS-PAGE
Conjugation
Notes : Universal Precautions. Safe laboratory practices should be used when handling this material.
Storage : Store at 4centigrade on dry atmosphere or store at -20centigrade for long term storage.After reconstitution, store at -20centigrade.Aliquot to avoid repeated freezing and thawing.
Storage Buffer : In 0.1M sodium phosphate buffer, 0.2M NaCl, pH 7.4 (0.09% sodium azide)
Gene Name : AFP alpha-fetoprotein [ Homo sapiens ]
Official Symbol : AFP
Synonyms : AFP; alpha-fetoprotein; HPAFP; FETA; alpha-fetoglobulin; alpha-1-fetoprotein;
Gene ID : 174
mRNA Refseq : NM_001134
Protein Refseq : NP_001125
MIM : 104150
UniProt ID : P02771

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (10)

Ask a question
Can AFP protein be utilized as a diagnostic or prognostic marker for certain diseases or conditions, and what experimental studies can be conducted to validate its clinical utility? 09/09/2022

The clinical utility of AFP protein as a diagnostic or prognostic marker can be validated through clinical studies using patient samples, correlation analyses with disease outcomes, or comparison with existing diagnostic methods.

What are the downstream signaling pathways or cellular responses triggered by AFP protein binding or activation, and how can they be studied using molecular and cellular techniques? 08/02/2022

Downstream signaling pathways or cellular responses triggered by AFP protein binding or activation can be studied using techniques such as Western blotting, gene expression analysis, or functional assays specific to the signaling pathways of interest.

Can AFP protein be targeted or manipulated to develop therapeutic interventions or treatment strategies, and what experimental approaches can be used to evaluate their efficacy and safety? 12/29/2021

Therapeutic interventions or treatment strategies targeting AFP protein can be evaluated for efficacy and safety using in vitro or in vivo models, disease-specific assays, or clinical trials to assess their impact on disease progression, patient outcomes, or potential side effects.

What are the cellular and molecular mechanisms underlying the production and secretion of AFP protein, and how can they be experimentally elucidated? 03/28/2021

The cellular and molecular mechanisms underlying the production and secretion of AFP protein can be elucidated through techniques such as gene expression analysis, protein trafficking studies, or immunofluorescence microscopy.

Are there any genetic variations or mutations in the AFP gene that impact its expression or function, and what are the implications for disease susceptibility or clinical outcomes? 07/22/2018

Genetic variations or mutations in the AFP gene that impact its expression or function can be investigated through genetic association studies, functional characterization of mutant variants, or population-based analyses.

What are the regulatory factors or signaling pathways that control the expression and transcriptional regulation of AFP gene, and how can their involvement be studied? 12/19/2017

The regulatory factors or signaling pathways that control the expression and transcriptional regulation of the AFP gene can be studied using techniques such as promoter analysis, transcription factor binding assays, or gene knockout/knockdown approaches.

What are the functional roles of AFP protein in embryonic development, tissue regeneration, or disease progression, and how can its biological functions be investigated experimentally? 04/30/2017

The functional roles of AFP protein in embryonic development, tissue regeneration, or disease progression can be investigated through genetic or pharmacological perturbations, in vitro or in vivo model systems, or functional assays specific to the biological processes of interest.

Are there any specific biomarkers or imaging techniques that can be used to detect AFP protein in biological samples, and how can their sensitivity and specificity be assessed experimentally? 09/21/2016

Specific biomarkers or imaging techniques for detecting AFP protein in biological samples can be developed and their sensitivity and specificity can be assessed using techniques such as ELISA, immunohistochemistry, or imaging modalities like MRI or PET.

How does AFP protein interact with its binding partners or ligands, and what experimental approaches can be used to study these interactions? 10/05/2015

The interactions of AFP protein with its binding partners or ligands can be studied using techniques such as co-immunoprecipitation, surface plasmon resonance, or receptor-binding assays.

How does AFP protein contribute to immunomodulation or immune evasion, and what experimental strategies can be employed to investigate its immune-related functions? 05/24/2015

The immune-related functions of AFP protein, such as immunomodulation or immune evasion, can be investigated using techniques like immune cell assays, cytokine profiling, or immune response assays.

Customer Reviews (3)

Write a review
Reviews
11/14/2022

    Investigating protein-protein interactions in cellular stress responses for cell survival.

    02/15/2020

      Dissecting protein-protein interactions in viral replication for antiviral strategies.

      03/09/2017

        Mapping protein-protein interactions in protein degradation pathways for proteostasis.

        Ask a Question for All AFP Products

        Required fields are marked with *

        My Review for All AFP Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends