Recombinant Active Human FGF1 Protein, His-tagged(C-ter)
Cat.No. : | FGF1-72H |
Product Overview : | Recombinant Active Human FGF1 Protein with His tag (C-ter) was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009] |
Source : | E. coli |
Species : | Human |
Tag : | His(C-ter) |
Form : | Powder |
Bio-activity : | Determined by its ability to induce 3T3 cells proliferation. The ED50 for this effect is < 0.3 ng/mL. The specific activity of recombinant human FGF-1 is > 1 x 10^6 IU/mg. |
AA Sequence : | MFNLPPGNYKKPKLLYCSNGGHFLR ILPDGTVDGTRDRSDQHIQLQLSAE SVGEVYIKSTETGQYLAMDTDGLLY GSQTPNEECLFLERLEENHYNTYIS KKHAEKNWFVGLKKNGSCKRGPRTH YGQKAILFLPLPVSSD |
Endotoxin : | Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. |
Purity : | > 98% (by SDS-PAGE) |
Applications : | SDS-PAGE |
Notes : | For laboratory research only, not for drug, diagnostic or other use. |
Storage : | Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Storage Buffer : | PBS (pH 8.0) |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
Gene Name : | FGF1 fibroblast growth factor 1 (acidic) [ Homo sapiens ] |
Official Symbol : | FGF1 |
Synonyms : | FGF1; fibroblast growth factor 1 (acidic); FGFA; fibroblast growth factor 1; AFGF; ECGF; ECGF beta; ECGFA; ECGFB; endothelial cell growth factor; alpha; beta; FGF alpha; GLIO703; HBGF1; heparin binding growth factor 1; heparin-binding growth factor 1; beta-endothelial cell growth factor; endothelial cell growth factor, beta; endothelial cell growth factor, alpha; FGF-1; HBGF-1; ECGF-beta; FGF-alpha; |
Gene ID : | 2246 |
mRNA Refseq : | NM_000800 |
Protein Refseq : | NP_000791 |
MIM : | 131220 |
UniProt ID : | P05230 |
Products Types
◆ Recombinant Protein | ||
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FGF1-1514R | Recombinant Rhesus Macaque FGF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Fgf1-057M | Active Recombinant Mouse Fgf1 Protein | +Inquiry |
FGF1-12H | Active Recombinant Human FGF1 Protein (Carry Free-Lyophilized, 140 amino acid) | +Inquiry |
Fgf1-4096R | Active Recombinant Rat Fgf1 Protein | +Inquiry |
◆ Native Protein | ||
FGF1-26203TH | Native Human FGF1 | +Inquiry |
FGF1-33B | Active Native Bovine FGF1 | +Inquiry |
◆ Lysates | ||
FGF1-6252HCL | Recombinant Human FGF1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, there have been clinical trials exploring the use of FGF1 in treating heart disease, specifically in promoting cardiac angiogenesis.
Yes, FGF1 is being investigated for its potential in regenerative medicine to repair damaged tissues and organs.
FGF1 has shown potential in improving insulin sensitivity and glucose regulation in preclinical studies, but further research is needed for clinical applications.
Safety concerns include the risk of uncontrolled cell growth, which could lead to cancer, and the need for precise dosing and administration.
Potential side effects may include inflammation at the application site, allergic reactions, and adverse effects related to uncontrolled cell growth.
Customer Reviews (3)
Write a reviewBy using FGF1 protein, I can explore the mechanisms underlying cell division, cell cycle control, and the molecular pathways associated with these processes.
The protein's interaction with other APC/C subunits enables the study of its function and the investigation of its involvement in various cellular processes.
As a researcher utilizing FGF1 protein in my trials, I can highlight its advantages and the valuable support provided by the manufacturer in facilitating my research.
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