FGF1

  • Official Full Name

    fibroblast growth factor 1 (acidic)

  • Overview

    Fibroblast growth factors, or FGFs, are a family of growth factors involved in angiogenesis, wound healing, and embryonic development. The FGFs are heparin-binding proteins and interactions with cell-surface associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. FGFs are key players in the processes of proliferation and differentiation of wide variety of cells and tissues.
  • Synonyms

    FGF1; Fibroblast Growth Factor-acidic; FGF-acidic; Basic fibroblast growth factor; BFGF; FGF 2; FGF B; FGF2; FGF2 basic; FGF2_HUMAN; FGFB; Fibroblast growth factor 2 (basic); HBGF 2; HBGF-2; HBGF2; HBGH 2; HBGH2; Heparin binding growth factor 2 precursor; Heparin-binding growth factor 2; Prostatropin;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Native Proteins
  • GMP Proteins
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Canine
  • Cattle
  • Chicken
  • Cynomolgus
  • Human
  • Mouse
  • Mouse/Rat
  • Pig
  • Rat
  • Rhesus Macaque
  • Sheep
  • Bovine Brain
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mouse
  • Oryza Sativa
  • Sf21 Insect Cell
  • Wheat Germ
  • yeast
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • His(C
  • ter)
  • His|GST
  • His|T7
  • SUMO
  • Met
  • Myc
  • DDK
  • MYC
  • N/A
  • N
  • Strep II
  • Tag free
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FGF1-021E Active Recombinant Human FGF1 (16-155aa), Met tagged E.coli N/A
Human FGF1-619H Active Recombinant Human FGF1, Met-tagged E.coli Met
Human FGF1-8498H Active Recombinant Human FGF1, His-tagged Sf21 Insect Cell His
Human FGF1-4H Active Recombinant Human Acidic Fibroblast Growth Factor yeast N/A
Human FGF1-2H Active Recombinant Human FGF-1, Acidic Insect Cell N/A
Human FGF1-244H Recombinant Human FGF1, StrepII-tagged Human Cell Strep II 16-155, 140 a.a.
Human FGF1-173H Recombinant Human Fibroblast Growth Factor 1 (acidic, Sf9 Insect Cells Derived) Insect Cell N/A
Human FGF1-12861H Recombinant Human FGF1, GST-tagged E.coli GST 1-155a.a.
Human FGF1-564H Recombinant Human FGF1 protein E.coli N/A 141
Human FGF1-199H Recombinant Human Acidic Fibroblast Growth Factor, His-tagged E.coli His
Human FGF1-09H Recombinant Human FGF1 protein E.coli N/A 154
Human FGF1-26555TH Recombinant Human FGF1, His-tagged His
Human FGF1-013O Recombinant Human FGF1 Oryza Sativa N/A
Human FGF1-255H Recombinant Human FGF1 protein E.coli N/A
Human FGF1-26204TH Recombinant Human FGF1, His-tagged His
Human FGF1-547H Recombinant Human FGF1 protein, His & GST-tagged E.coli His/GST Met1~Asp155
Human FGF1-6252HCL Recombinant Human FGF1 293 Cell Lysate HEK293 N/A
Human FGF1-828H Recombinant Human FGF1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FGF1-26203TH Native Human FGF1 E.coli N/A
Human FGF1-5960H Recombinant Human FGF1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FGF1-4094H Recombinant Human FGF1 Protein, GST-tagged Wheat Germ GST
Human FGF1-2902H Recombinant Human FGF1 protein, His-SUMO-tagged E.coli His-SUMO 16-155aa
Human FGF1-1260H Recombinant Human FGF1 protein, His-tagged E.coli His Phe16~Asp155
Human FGF1-2903H Recombinant Human FGF1 protein, His-tagged E.coli His 16-155aa
Human FGF1-322H Recombinant Human FGF1 protein E.coli Phe16-Asp155
Human FGF1-404F Active Recombinant Human FGF1 Protein (140 aa) E.coli 140
Human FGF1-0272H Active Recombinant Human FGF1 protein E.coli N/A Phe16-Asp155
Human FGF1-4807HF Recombinant Full Length Human FGF1 Protein, GST-tagged In Vitro Cell Free System GST 155 amino acids
Human FGF1-5231H Recombinant Human FGF1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FGF1-12H Active Recombinant Human FGF1 Protein (Carry Free-Lyophilized, 140 amino acid) E.coli 140 amino acid
Human FGF1-043H Active Recombinant Human FGF1 Protein E.coli
Human FGF1-72H Recombinant Active Human FGF1 Protein, His-tagged(C-ter) E.coli His(C-ter)
Human FGF1-038H Recombinant Human FGF1 Protein E.coli 822
Human FGF1-10H Active Recombinant Human FGF1 Protein (Carry Free-Ready-To-Use, 140 amino acid) E.coli 140 amino acid
Human FGF1-77H Active Recombinant Human FGF1 Protein E.coli
Human FGF1-2527H Recombinant Human FGF1 Protein (Met1-Asp155), C-His tagged E.coli C-His Met1-Asp155
Human FGF1-11H Active Recombinant Human FGF1 Protein (Carrier-Ready-To-Use, 140 amino acid) E.coli 140 amino acid
Human FGF1-2528H Recombinant Human FGF1 Protein (Phe16-Asp155) E.coli Tag Free Phe16-Asp155
Human FGF1-161H Active Recombinant Human FGF1 Protein E.coli Tag Free
Human FGF1-93H Active Recombinant Human FGF1 Protein (Phe16-Asp155), C-His tagged, Animal-free, Carrier-free E.coli C-His Phe16-Asp155
Human FGF1-81H Recombinant Human FGF1 Protein E.coli Tag free
Human FGF1-4344HG Active GMP Recombinant Human FGF1 protein E.coli N/A
Mouse Fgf1-565M Active Recombinant Mouse Fibroblast Growth Factor 1 E.coli N/A
Mouse Fgf1-634M Active Recombinant Mouse Fgf1 E.coli Met Phe16-Asp155
Mouse Fgf1-558M Recombinant Mouse Fgf1 protein E.coli N/A 140
Mouse Fgf1-496M Recombinant Mouse Fgf1, His-tagged Mouse His
Mouse Fgf1-572M Recombinant Mouse Fgf1, None tagged E.coli N/A
Mouse Fgf1-10M Recombinant Mouse Fibroblast Growth Factor-acidic E.coli N/A
Mouse FGF1-5837M Recombinant Mouse FGF1 Protein Mammalian Cell His
Mouse Fgf1-403F Active Recombinant Mouse Fgf1 Protein (140 aa) E.coli 140
Mouse Fgf1-5666M Recombinant Mouse Fgf1 Protein (Phe16-Asp155), C-His tagged E.coli C-His Phe16-Asp155
Mouse FGF1-3224M-B Recombinant Mouse FGF1 Protein Pre-coupled Magnetic Beads HEK293
Mouse FGF1-3224M Recombinant Mouse FGF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Fgf1-7205M Recombinant Mouse Fgf1 Protein, His-tagged E.coli His 16-155
Mouse Fgf1-056M Active Recombinant Mouse Fgf1 Protein E.coli
Mouse Fgf1-057M Active Recombinant Mouse Fgf1 Protein E.coli
Mouse Fgf1-058M Recombinant Mouse Fgf1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat Fgf1-257R Recombinant Rat Fgf1 protein E.coli N/A
Rat FGF1-2323R Recombinant Rat FGF1 Protein Mammalian Cell His
Rat Fgf1-631R Recombinant Rat Fgf1 protein, His & GST-tagged E.coli His/GST Phe16~Asp155 (Accession # P61149)
Rat FGF1-1980R Recombinant Rat FGF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Fgf1-4096R Active Recombinant Rat Fgf1 Protein E.coli N/A
Rat Fgf1-6840R Recombinant Rat Fgf1 Protein (Phe16-Asp155) E.coli Tag Free Phe16-Asp155
Rat FGF1-1980R-B Recombinant Rat FGF1 Protein Pre-coupled Magnetic Beads HEK293
Bovine FGF1-33B Active Native Bovine FGF1 Bovine Brain N/A
Canine FGF1-159C Active Recombinant Canine FGF1 protein E.coli N/A Phe16-Asp155
Cattle FGF1-928C Recombinant Cattle FGF1 Protein, His-tagged E.coli N-His Pro42-Asp155
Cynomolgus FGF1-65C Recombinant Cynomolgus FGF1 protein(Phe16-Asp155) E.coli N/A Phe16-Asp155
Mouse/Rat FGF1-78M Recombinant Mouse/Rat FGF1 Protein E.coli
Mouse/Rat FGF1-79M Recombinant Mouse/Rat FGF1 Protein E.coli
Rhesus Macaque FGF1-1692R Recombinant Rhesus monkey FGF1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque FGF1-1514R Recombinant Rhesus Macaque FGF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque FGF1-1514R-B Recombinant Rhesus Macaque FGF1 Protein Pre-coupled Magnetic Beads HEK293
Sheep FGF1-629S Recombinant Sheep FGF1 protein, His & T7-tagged E.coli His/T7 Ala2~Asp155 (Accession # Q7M303)
Pig FGF1-630P Recombinant Pig FGF1 protein, His & GST-tagged E.coli His/GST Leu12~Pro151 (Accession # P20002)
Chicken FGF1-6735C Recombinant Chicken FGF1 Mammalian Cell His
Chicken FGF1-6736C Recombinant Chicken FGF1 protein, His-tagged E.coli His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • FGF1 Related Signal Pathway

FGF1 involved in several pathways and played different roles in them. We selected most pathways FGF1 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayPRKACAA;MAP3K6;RPS6KA3B;FGF16;FGFR2;HSPA1L;CASP3A;NTRK2B;CD14
Ras signaling pathwayBAD;CALM1;FGF2;PDGFC;KITLG;FOXO4;FGF16;GRIN1;PGF
Rap signaling pathwayRASSF5;FARP2;FIGF;VEGFB;MET;FGF1;GNAI3;Kitl;CALML3
PIK-Akt signaling pathwayEPO;MTCP1;NGF;FGF7;F2R;FGF1;IL6R;ITGA10;IL6
Hippo signaling pathwayWNT3;Fzd4;FZD3;LLGL2;TEAD3;PRKCI;BMPR1B;MOB1A;PARD3
Regulation of actin cytoskeletonMYL1;PFN1;PIK3CB;INS2;ARHGEF4;MYH9;ACTN2B;BCAR1;FGF3
Pathways in cancerMSH6;TP53;FGF14;GNB3;CDC42;KIT;GNG13;STAT5B;FGF7
MelanomaFGF11;TP53;ARAF;FGF19;MET;PIK3R1;PIK3R2;NRAS;BAD

FGF1 has several biochemical functions, for example, S100 protein binding, fibroblast growth factor receptor binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF1 itself. We selected most functions FGF1 had, and list some proteins which have the same functions with FGF1. You can find most of the proteins on our site.

Function Related Protein
S100 protein bindingS100A11;S100B;FGF1A;EZR;ANXA11;AHNAK;DDX1;ATP2A2;ANXA2
fibroblast growth factor receptor bindingFGF2;FGF20B;FGF1;FGF6A;FGF10;FGF1A;FGF3;FGF5;FRS2
growth factor activityLEFTY2;MIA1;GSDF;NDP;VEGFC;KLK1B3;OGN;NDR2;FGF6A
heparin bindingCTGFA;SELL;SERPINA10;ZFP207;MMP7;THBS2;ADAMTS3;PCOLCE2;CCL2
protein bindingMYLIPA;OSTB;CALU;WDR20;SH2D3A;VCAN;PTRH2;IGF2;SSR1

FGF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF1.

FGFR1; FGFR2; heparin; intg_av_b3_human; FGFR3; copper(2+); SRPK1; FGFR4; HSPG2

Research Area

Related articles

Tiede, C; Tang, AAS; et al. Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications. PROTEIN ENGINEERING DESIGN & SELECTION 27:145-155(2014).
Aizman, I; Tirumalashetty, BJ; et al. Comparison of the neuropoietic activity of gene-modified versus parental mesenchymal stromal cells and the identification of soluble and extracellular matrix-related neuropoietic mediators. STEM CELL RESEARCH & THERAPY 5:-(2014).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
Are there any clinical trials using FGF1 for heart disease? 06/28/2020

Yes, there have been clinical trials exploring the use of FGF1 in treating heart disease, specifically in promoting cardiac angiogenesis.

Can FGF1 be used in regenerative medicine? 09/15/2018

Yes, FGF1 is being investigated for its potential in regenerative medicine to repair damaged tissues and organs.

Can FGF1 be used in the treatment of diabetes? 03/29/2018

FGF1 has shown potential in improving insulin sensitivity and glucose regulation in preclinical studies, but further research is needed for clinical applications.

What safety concerns are associated with FGF1 use? 01/15/2017

Safety concerns include the risk of uncontrolled cell growth, which could lead to cancer, and the need for precise dosing and administration.

Are there any side effects associated with FGF1 therapy? 12/10/2016

Potential side effects may include inflammation at the application site, allergic reactions, and adverse effects related to uncontrolled cell growth.

Customer Reviews (3)

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Reviews
08/06/2021

    By using FGF1 protein, I can explore the mechanisms underlying cell division, cell cycle control, and the molecular pathways associated with these processes.

    06/03/2021

      The protein's interaction with other APC/C subunits enables the study of its function and the investigation of its involvement in various cellular processes.

      11/25/2018

        As a researcher utilizing FGF1 protein in my trials, I can highlight its advantages and the valuable support provided by the manufacturer in facilitating my research.

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