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Recombinant Active Human IFNL3 Protein, His-tagged(C-ter)

Cat.No. : IFNL3-123H
Product Overview : Recombinant Active Human IFNL3 Protein with His tag (C-ter) was expressed in E. coli.
  • Specification
  • Gene Information
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Description : This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]
Source : E. coli
Species : Human
Tag : His(C-ter)
Form : Powder
Bio-activity : Determined by its ability to protect HepG2 cells infected with encephalomyocarditis (EMC) virus. The ED50 for this effect is < 5 ng/mL.
AA Sequence : MVPVARLRGALPDARGCHIAQFKSL SPQELQAFKRAKDALEESLLLKDCK CRSRLFPRTWDLRQLQVRERPVALE AELALTLKVLEATADTDPALGDVLD QPLHTLHHILSQLRACIQPQPTAGP RTRGRLHHWLHRLQEAPKKESPGCL EASVTFNLFRLLTRDLNCVASGDLC V
Endotoxin : Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test.
Purity : > 95% (by SDS-PAGE)
Applications : SDS-PAGE
Notes : For laboratory research only, not for drug, diagnostic or other use.
Storage : Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
Storage Buffer : PBS (pH 8.0)
Reconstitution : It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
Gene Name : IFNL3 interferon lambda 3 [ Homo sapiens (human) ]
Official Symbol : IFNL3
Synonyms : IFNL3; interferon lambda 3; IL28B; IL28C; IL-28B; IL-28C; IFN-lambda-3; IFN-lambda-4; interferon lambda-3; cytokine Zcyto22; interferon, lambda 4; interleukin-28B; interleukin-28C
Gene ID : 282617
mRNA Refseq : NM_172139
Protein Refseq : NP_742151
MIM : 607402
UniProt ID : Q8IZI9

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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