Recombinant Active Human IL17A Protein, His-tagged(C-ter)
Cat.No. : | IL17A-148H |
Product Overview : | Recombinant Active Human IL17A Protein with His tag (C-ter) was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008] |
Source : | E. coli |
Species : | Human |
Tag : | His(C-ter) |
Form : | Powder |
Bio-activity : | Determined by its ability to induce IL-6 secretion in 3T3 cells. The ED50 for this effect is <6 ng/mL. |
AA Sequence : | MIVKAGITIPRNPGCPNSEDKNFPR TVMVNLNIHNRNTNTNPKRSSDYYN RSTSPWNLHRNEDPERYPSVIWEAK CRHLGCINADGNVDYHMNSVPIQQE ILVLRREPPHCPNSFRLEKILVSVG CTCVTPIVHHVA |
Endotoxin : | Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. |
Purity : | > 98% (by SDS-PAGE) |
Applications : | SDS-PAGE |
Notes : | For laboratory research only, not for drug, diagnostic or other use. |
Storage : | Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Storage Buffer : | PBS (pH 8.0) |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
Gene Name : | IL17A interleukin 17A [ Homo sapiens ] |
Official Symbol : | IL17A |
Synonyms : | IL17A; interleukin 17A; CTLA8, IL17, interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8); interleukin-17A; cytotoxic T lymphocyte associated protein 8; IL 17; IL 17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; cytotoxic T-lymphocyte-associated serine esterase 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); IL17; CTLA8; IL-17; IL-17A; |
Gene ID : | 3605 |
mRNA Refseq : | NM_002190 |
Protein Refseq : | NP_002181 |
MIM : | 603149 |
UniProt ID : | Q16552 |
Products Types
◆ Recombinant Protein | ||
IL17A-254I | Active Recombinant Human IL17A Protein (142 aa), His-tagged | +Inquiry |
IL17A-139M | Active Recombinant Mouse IL17A Protein | +Inquiry |
IL17A-508M | Recombinant Mouse IL17A Protein | +Inquiry |
IL17A-137H | Active Recombinant Human IL17A Protein | +Inquiry |
IL17A-27H | Active Recombinant Human IL17A Protein, Animal Free | +Inquiry |
◆ Lysates | ||
IL17A-001HCL | Recombinant Human IL17A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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