IL17A Protein

IL17A

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IL17A

Official Full Name interleukin 17A
Background The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
Synonyms IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8);
    • Species :
    • Bovine
    • Canine
    • Chicken
    • Cynomolgus
    • Cynomolgus monkey
    • Dog
    • Equine
    • Human
    • Marmoset
    • Mouse
    • Ovine
    • Pig
    • Porcine
    • Rabbit
    • Rat
    • Rhesus Macaque
    • Source :
    • Baculovirus-Insect Cells
    • CHO
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Human Cell
    • Human cells
    • Insect Cell
    • Mammalian Cell
    • Mammalian cells
    • Rat
    • Yeast
    • Tag :
    • Alexa Fluor 488
    • Fc
    • Flag
    • GST
    • His
    • His(C-ter)
    • T7
    • His-Avi
    • Myc/DDK
    • N/A
    • N-His
    • Strep II
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL17A&IL17F-165H Active Recombinant Human IL17A/IL17F Protein, Biotinylated CHO N/A Inquiry
    Human IL17A-113H Active Recombinant Human Interleukin 17A HEK293 N/A Inquiry
    Human IL17A-166H Active Recombinant Human IL17A Protein, Biotinylated HEK293 N/A Inquiry
    Human IL17A-307H Active Recombinant Human IL17A CHO N/A Inquiry
    Human IL17A-333H Active Recombinant Human IL17A Human N/A Inquiry
    Human IL17A-487H Active Recombinant Human Interleukin 17A E.coli N/A Inquiry
    Human IL17A-570H Active Recombinant Human Interleukin 17A, MIgG2a Fc-tagged CHO Fc Inquiry
    Human IL17A-571H Active Recombinant Human Interleukin 17A, HIgG1 Fc-tagged, mutant CHO Fc Inquiry
    Human IL17A-572H Active Recombinant Human Interleukin 17A, HIgG1 Fc-tagged CHO Fc Inquiry
    Mouse IL17A-001H Active Recombinant Mouse Interleukin 17A, MIgG2a Fc-tagged CHO Fc Inquiry
    Mouse IL17A-588M Active Recombinant Mouse Interleukin 17A, MIgG2a Fc-tagged, mutant CHO Fc Inquiry
    Rat Il17a-680R Active Recombinant Rat Il17a CHO N/A Inquiry
    Marmoset IL17A-425M Active Recombinant Marmoset IL17A E.coli N/A Inquiry
    Human IL17A-491H Active Recombinant Human IL-17A Protein, His-tagged HEK293 His Inquiry
    Mouse Il17a-01M Active Recombinant Mouse Il17a Protein, His-Tagged E.coli His Inquiry
    Rhesus Macaque IL17A&IL17F-262R Recombinant Rhesus IL17A/IL17F protein, His-tagged HEK293 His Inquiry
    Rhesus Macaque IL17A-261R Recombinant Rhesus IL17A protein Insect Cell N/A Inquiry
    Human IL17A-122H Recombinant Human IL17A protein E.coli N/A Inquiry
    Human IL17A-14153H Recombinant Human IL17A, GST-tagged E.coli GST Inquiry
    Human IL17A-26H Recombinant Human Interleukin-17 E.coli N/A Inquiry
    Human IL17A-279H Recombinant Human Interleukin 17A, Fc Chimera Mammalian Cell Fc Inquiry
    Human IL17A-28212TH Recombinant Human IL17A, Fc-tagged HEK293 Fc Inquiry
    Human IL17A-288H Recombinant Human IL17A, StrepII-tagged Human Cell Strep II Inquiry
    Human IL17A-426H Recombinant Human Interleukin 17A, His-tagged Human His Inquiry
    Human IL17A-445H Recombinant Human IL17A Protein, His-tagged Yeast His Inquiry
    Human IL17A-63H Recombinant Human IL17A, His-tagged Insect Cell His Inquiry
    Human IL17A-7334H Recombinant Human IL17A, His tagged Insect Cell His Inquiry
    Human IL17A-7335H Recombinant Human IL17A, None tagged E.coli N/A Inquiry
    Human IL17A-870H Recombinant Human IL17A protein, His & T7-tagged E.coli His/T7 Inquiry
    Human IL17A-97H Recombinant Human IL-17A Yeast N/A Inquiry
    Mouse Il17a-105M Recombinant Mouse Il17a, None tagged E.coli N/A Inquiry
    Mouse Il17a-12M Recombinant Mouse Il17a Yeast N/A Inquiry
    Mouse Il17a-334M Recombinant Mouse Il17a, His-tagged E.coli His Inquiry
    Mouse Il17a-71M Recombinant Mouse Interleukin 17A E.coli N/A Inquiry
    Rat Il17a-489R Recombinant Rat Il17a protein E.coli N/A Inquiry
    Rat Il17a-492R Recombinant Rat Interleukin-17AF Heterodimer E.coli N/A Inquiry
    Rat Il17a-871R Recombinant Rat Il17a protein, His-tagged E.coli His Inquiry
    Rat Il17a-89R Recombinant Rat Interleukin 17A E.coli N/A Inquiry
    Canine IL17A-168C Recombinant Canine IL17A E.coli N/A Inquiry
    Dog IL17A-868D Recombinant Dog IL17A protein, His & T7-tagged E.coli His/T7 Inquiry
    Canine IL17A-96C Recombinant Canine IL-17A Yeast N/A Inquiry
    Bovine IL17A-236B Recombinant Bovine Interleukin 17A Yeast N/A Inquiry
    Chicken IL17A-869C Recombinant Chicken IL17A protein, His & GST-tagged E.coli His/GST Inquiry
    Rabbit IL17A-872R Recombinant Rabbit IL17A protein, His-tagged E.coli His Inquiry
    Marmoset IL17A-153M Recombinant Marmoset IL17A E.coli N/A Inquiry
    Equine IL17A-254E Recombinant Equine Interleukin 17A Yeast N/A Inquiry
    Ovine IL17A-98O Recombinant Ovine IL-17A Yeast N/A Inquiry
    Human IL17A-001HCL Recombinant Human IL17A cell lysate Human Cell N/A Inquiry
    Mouse Il17a-678M-B Recombinant Mouse Il17a protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Inquiry
    Porcine IL17A-01P GMP Recombinant Porcine IL17A Protein, His-Tagged E.coli His Inquiry
    Cynomolgus IL17A-055C Recombinant Cynomolgus IL17A(Gly24­Ala155) Protein, C-6*His-tagged HEK293 His Inquiry
    Pig IL17A-1008P Recombinant Pig IL17A Protein, His-tagged E.coli N-His Inquiry
    Human IL17A-102H Recombinant Human IL17A Protein E.coli Inquiry
    Human IL17A-116H Recombinant Human IL17A Protein, His-tagged Human Cell His Inquiry
    Canine IL17A-12C Recombinant Canine IL17A Protein, His-tagged HEK293 His Inquiry
    Human IL17A-137H Recombinant Human IL17A Protein E.coli Inquiry
    Human IL17A-138H Recombinant Human IL-17AF Heterodimer Protein E.coli Inquiry
    Mouse IL17A-139M Recombinant Mouse IL17A Protein E.coli Inquiry
    Mouse IL17A-140M Recombinant Mouse IL-17AF Heterodimer Protein E.coli Inquiry
    Rat IL17A-141R Recombinant Rat IL17A Protein E.coli Inquiry
    Rat IL17A-142R Recombinant Rat IL-17AF Heterodimer Protein E.coli Inquiry
    Human IL17A-148H Recombinant Active Human IL17A Protein, His-tagged(C-ter) E.coli His(C-ter) Inquiry
    Mouse Il17a-149M Recombinant Active Mouse IL17A Protein, His-tagged(C-ter) E.coli His(C-ter) Inquiry
    Human IL17A-2293H Recombinant Human IL17A Protein, His-tagged E.coli N-His Inquiry
    Human IL17A-27H Recombinant Human IL17A Protein, Animal Free Human cells Inquiry
    Rhesus macaque IL17A-3092R Recombinant Rhesus macaque IL17A protein, GST-tagged E.coli GST Inquiry
    Rabbit IL17A-3093R Recombinant Rabbit IL17A protein, GST-tagged E.coli GST Inquiry
    Human IL17A-48H Recombinant Human IL17A Protein E.coli Inquiry
    Rabbit IL17A-5438R Recombinant Rabbit IL17A protein, His-tagged Yeast His Inquiry
    Human IL17A-57H Recombinant Human IL17A Protein, GST-tagged E.coli GST Inquiry
    Human IL17A-903HFL Recombinant Full Length Human IL17A Protein, C-Flag-tagged Mammalian cells Flag Inquiry
    Human IL17A & IL17F-01H Recombinant Human IL17A & IL17F protein, His-Avi-tagged HEK293 His-Avi Inquiry
    Human IL17A-381HB Recombinant Human IL17A protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Inquiry
    Human IL17A-4331HG GMP Recombinant Human IL17A protein E.coli N/A Inquiry
    Human IL17A-547H Recombinant Human IL17A Protein (Ile20-Ala155), Met, Biotinylated E.coli N/A Inquiry
    Human IL17A-5856H Recombinant Human IL17A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK Inquiry
    Human IL17A-5H Human Interleukin-17 Reference standard N/A Inquiry
    Mouse DMABT-H18989 Rat Anti-IL17A Monoclonal Antibody Rat Alexa Fluor 488 Inquiry
    Mouse Il17a-093M Recombinant Mouse Il17a Protein E.coli Inquiry
    Mouse Il17a-094M Recombinant Mouse Il17a Protein E.coli Inquiry
    Mouse Il17a-095M Recombinant Mouse Il17a Protein E.coli Inquiry
    Mouse Il17a-096M Recombinant Mouse Il17a Protein, MYC/DDK-tagged HEK293T MYC/DDK Inquiry
    Mouse IL17A-381M Recombinant Mouse IL17A Protein, His-tagged HEK293 His Inquiry
    Mouse Il17a-678M Recombinant Mouse Il17a protein, His-Avi-tagged HEK293 His-Avi Inquiry
    Mouse IL17A-848M Recombinant Mouse IL17A Protein (Ala26-Ala158) Yeast N/A Inquiry
    Cynomolgus monkey IL17A-001C Recombinant Cynomolgus Monkey IL17A Protein Yeast N/A Inquiry
    Cynomolgus IL17A-002C Recombinant Cynomolgus IL17A protein (Met1-Ala155) Baculovirus-Insect Cells Inquiry
    Cynomolgus IL17A-056C Recombinant Cynomolgus IL17A protein, His-Avi-tagged HEK293 His-Avi Inquiry
    Rabbit IL17A-440R Recombinant Rabbit IL17 Protein, His-tagged Insect Cell His Inquiry
    Rabbit IL17A-441R Recombinant Rabbit IL17 Protein, His-tagged E.coli His Inquiry

    IL17A involved in several pathways and played different roles in them. We selected most pathways IL17A participated on our site, such as Cytokine-cytokine receptor interaction, Inflammatory bowel disease (IBD), Rheumatoid arthritis, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL17A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction EDA; BMPR2; GH2; PRP2; IFNL3; CCL21; IL19; GHRA; IFNGR1; MPL
    Inflammatory bowel disease (IBD) HLA-DRB4; HLA-DMB; IL12RB1; HLA-DQB1; TLR4; HLA-DPB1; HLA-DRA; Il4ra; IL4R; IFNG
    Rheumatoid arthritis ATP6V1G2; VEGFA; CXCL6; ATP6V1B1; ATP6V0E; IL1A; ATP6V0E2; CCL20; ITGAL; CCL5

    IL17A has several biochemical functions, for example, cytokine activity, cytokine receptor binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL17A itself. We selected most functions IL17A had, and list some proteins which have the same functions with IL17A. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity IL18; Il23a; Il12b; CMTM7; VEGFA; NAMPT; CMTM6; SPP1; INHBA; IFN-a; IL10
    cytokine receptor binding IL17B; IFNT2; Ifna11; IFNA21; IFNA8; IL17A/F2; IFN-a; IL17A; IFNPHI4; IFNA13
    protein binding SPG7; APOBEC3H; FRK; HMGB4; TXNIP; TRPC4AP; ATF7IP; BRD9; TRAF1; FAT4

    IL17A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL17A here. Most of them are supplied by our site. Hope this information will be useful for your research of IL17A.

    DPH2

    Mease, PJ; et al. Inhibition of interleukin-17, interleukin-23 and the TH17 cell pathway in the treatment of psoriatic arthritis and psoriasis. CURRENT OPINION IN RHEUMATOLOGY 27:127-133(2015).
    Ji, PY; Hu, HL; et al. AcCystatin, an immunoregulatory molecule from Angiostrongylus cantonensis, ameliorates the asthmatic response in an aluminium hydroxide/ovalbumin-induced rat model of asthma. PARASITOLOGY RESEARCH 114:613-624(2015).

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