Recombinant Bacillus subtilis AMPS protein, His-tagged

• Cat.No.: AMPS-1855B
• Product Overview: Recombinant Bacillus subtilis AMPS full length or partial length protein was expressed.

Specification

• Source: E. coli or Yeast
• Species: Bacillus subtilis
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: > 80% by SDS-PAGE
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
• Storage buffer: PBS buffer

Gene Information

• Gene Name: ampS aminopeptidase AmpS [ Bacillus subtilis subsp. subtilis str. 168 ]
• Official Symbol: AMPS
• Synonyms: AMPS; aminopeptidase AmpS
• Gene ID: 938756
• UniProt ID: P39762

Reviews

09/03/2019

I enthusiastically recommend the AMPS protein to fellow researchers who seek an unparalleled product accompanied by dedicated customer assistance.

02/16/2019

The remarkable quality and reliability of the AMPS protein have significantly contributed to the success of my structural investigations.

01/23/2019

the AMPS protein has proven to be invaluable in protein electron microscopy structure analysis.

07/03/2017

I must applaud the AMPS protein for its outstanding performance in Western blotting experiments.

01/09/2016

I highly recommend the AMPS protein for a variety of experimental applications.

Q&As

Can AMPS protein be used for developing new antimicrobial therapies?

The knowledge gained from studying AMPS proteins and their interactions with antimicrobial peptides has the potential to contribute to the development of new antimicrobial therapies. By understanding the mechanisms by which AMPS proteins activate immune responses, scientists may be able to design drugs or vaccines that can enhance the body's natural defense against pathogens and help combat antimicrobial resistance.

What are some examples of AMPS proteins?

There are several examples of AMPS proteins found in different organisms. For example, in humans, one of the well-known AMPS proteins is called hCAP18 (human cathelicidin antimicrobial peptide 18). In plants, there are various types of AMPS proteins, such as defensins and thionins. Bacteria also have AMPS proteins, and examples include the Escherichia coli protein SbmA, which is involved in the transport and sensing of antimicrobial peptides.

Are there any diseases or conditions associated with AMPS protein dysregulation?

AMPS protein dysregulation has been implicated in various diseases and conditions. For instance, abnormal expression or function of AMPS proteins can contribute to immune deficiencies, increased susceptibility to infections, or chronic inflammatory disorders. Additionally, mutations or alterations in the genes encoding AMPS proteins could lead to genetic disorders associated with impaired immune defense.

How does AMPS protein function?

AMPS proteins serve as sensors for antimicrobial peptides, which are small molecules that can kill or inhibit the growth of microorganisms. When AMPS proteins detect the presence of AMPs, they initiate a signaling cascade that leads to the activation of immune responses against pathogens. These responses can include the production of antimicrobial compounds, increased expression of immune-related genes, and recruitment of immune cells to the site of infection.

Are there any ongoing research studies focused on AMPS protein?

Yes, there are ongoing research studies focused on AMPS proteins in various organisms. Scientists are investigating the molecular mechanisms by which AMPS proteins recognize antimicrobial peptides and activate immune responses. Additionally, researchers are studying how AMPS proteins can be targeted and modulated to enhance immune defense against pathogens or to develop new antimicrobial therapies.

Can AMPS proteins be used as diagnostic markers?

Yes, AMPS proteins have the potential to be used as diagnostic markers for certain conditions. For example, the expression of hCAP18, an AMPS protein in humans, has been associated with various inflammatory diseases and infections. Detecting the levels of hCAP18 in the blood or other body fluids could potentially aid in diagnosis, prognosis, or monitoring the progression of these conditions.

Can AMPS proteins have roles beyond antimicrobial defense?

Yes, AMPS proteins have been found to have roles beyond antimicrobial defense. Some studies suggest that certain AMPS proteins may have immunomodulatory functions, influencing the activation and regulation of immune responses. Additionally, AMPS proteins have been implicated in wound healing, tissue regeneration, and even cancer progression, indicating their potential involvement in various biological processes. However, further research is needed to fully understand the extent of their roles in these contexts.