Recombinant CRM197
Cat.No. : | CRM197-2780C |
Product Overview : | Recombinant CRM197is expressed in Pseudomonas fluorescens. MW = 58.4 kDa. |
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Cat. No. : | CRM197-2780C |
Description : | CRM197 is a non-toxic mutant of diphtheria toxin1,2 having a single amino acid substitution of glutamic acid for glycine. CRM197 is a well defined protein and functions as a carrier for polysaccharides and haptens making them immunogenic. It is utilized as a carrier protein in a number of approved conjugate vaccines for diseases such as meningitis and pneumococcal bacterial infections. |
Source : | Pseudomonas fluorescens. |
Endotoxin : | < 100 EU/mg of protein by LAL method. |
Purity : | > 95% CRM197 by SDS-PAGE. A and B chain content < 5% of total CRM197. |
Dimer : | < 5%. |
Storage and use : | CRM197 is lyophilized from a 0.2 μm-filtered solution containing 4 mg/mL CRM197, 50 mg/mL sucrose, 0.22 mg/mL sodium phosphate monobasic, 3 mg/mL sodium phosphate dibasic, 0.055 mg/mL polysorbate 80. Store at 2-8°C upon receipt. Before use, aseptically reconstitute lyophilized CRM197 with sterile deionized water to a concentration of 4 mg/mL CRM197. Reconstituted CRM197 should be stored at 2-8°C. |
Tag : | Non |
Gene Name : | tox diphtheria toxin precursor [ Corynebacterium diphtheriae NCTC 13129 ] |
Synonyms : | Tox; diphtheria toxin precursor; EC 2.4.2.36 |
Gene ID : | 2650491 |
Protein Refseq : | NP_938615 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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