| Species : |
E.coli |
| Source : |
E.coli |
| Tag : |
Non |
| Description : |
Ferric Uptake Regulator protein NCBI Accession No.: NP_415209 is a DNA-binding protein which controls iron-responsive genes. Ferric Uptake Regulator has a molecular mass of 17-kDa and plays a role in global transcriptional repressor that in the existence of iron regulates functions as diverse as iron acquisition, oxidative stress, and virulence. In Escherichia coli, members of the Ferric Uptake Regulator family regulate the expression of at least 100 genes that function in processes as diverse as the biosynthesis and transport of siderophores, the expression of virulence factors, the alleviation of oxidative and NO-induced stress, and the inhibition of ferritin production through the expression of RyhB. |
| Form : |
The Ferric Uptake Regulator protein solution contains 20mM Tris pH-8, 2mM CaCl2, and 100mM NaCl. |
| Purity : |
Greater than 90.0% as determined by (a) Analysis by RP-HPLC; (b) Analysis by SDS-PAGE. |
| Physical Appearance : |
Sterile Filtered colorless solution. |
| Amino Acid Sequence : |
MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYK RLIDMGEEIGLATVYRVLNQFDDAGIVTRHNFEG GKSVFELTQQHHHDHLICLDCGKVIEFSDDSIEARQ REIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHEGK. |
| Storage : |
Ferric Uptake Regulator although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Functions : |
transcription repressor activity |
