Recombinant Full Length Human ANXA2 Protein, C-Flag-tagged

• Cat.No.: ANXA2-591HFL
• Product Overview: Recombinant Full Length Human ANXA2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 38.4 kDa
• AA Sequence: MSTVHEILCKLSLEGDHSTPPSAYG SVKAYTNFDAERDALNIETAIKTKG VDEVTIVNILTNRSNAQRQD IAFAYQRRTKKELASALKSALSGHL ETVILGLLKTPAQYDASELKASMKG LGTDEDSLIEIICSRTNQEL QEINRVYKEMYKTDLEKDIISDTSG DFRKLMVALAKGRRAEDGSVIDYEL IDQDARDLYDAGVKRKGTDV PKWISIMTERSVPHLQKVFDRYKSY SPYDMLESIRKEVKGDLENAFLNLV QCIQNKPLYFADRLYDSMKG
  KGTRDKVLIRIMASRSEVDMLKIRS EFKRKYGKSLYYYIQQDTKGDYQKA LLYLCGGDDTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Secreted Protein, Stem cell - Pluripotency

Gene Information

• Gene Name: ANXA2 annexin A2 [ Homo sapiens (human) ]
• Official Symbol: ANXA2
• Synonyms: P36; ANX2; LIP2; LPC2; CAL1H; LPC2D; ANX2L4; PAP-IV; HEL-S-270
• Gene ID: 302
• mRNA Refseq: NM_001002857.2
• Protein Refseq: NP_001002857.1
• MIM: 151740
• UniProt ID: P07355