Recombinant Full Length Human CASP4 Protein, N-His-tagged
Cat.No. : | CASP4-921HFL |
Product Overview : | Recombinant Full Length Human CASP4 Protein, fused to His-tag at N-terminus, was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. |
Molecular Mass : | 43.1 kDa |
AA Sequence : | A DNA sequence encoding human full-length CASP4. |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, Protease |
Gene Name : | CASP4 caspase 4 [ Homo sapiens (human) ] |
Official Symbol : | CASP4 |
Synonyms : | TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II |
Gene ID : | 837 |
mRNA Refseq : | NM_001225.4 |
Protein Refseq : | NP_001216.1 |
MIM : | 602664 |
UniProt ID : | P49662 |
Products Types
◆ Recombinant Protein | ||
Casp4-626R | Recombinant Rat Casp4 Protein, His-tagged | +Inquiry |
CASP4-2594H | Recombinant Human CASP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
CASP4-01H | Active Recombinant Human CASP4 Protein | +Inquiry |
CASP4-0424H | Recombinant Human CASP4 Protein, GST-Tagged | +Inquiry |
CASP4-1244M | Recombinant Mouse CASP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CASP4-7837HCL | Recombinant Human CASP4 293 Cell Lysate | +Inquiry |
CASP4-7836HCL | Recombinant Human CASP4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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