Recombinant Full Length Human GSTP1 Protein, C-Flag-tagged

• Cat.No.: GSTP1-1202HFL
• Product Overview: Recombinant Full Length Human GSTP1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 23.2 kDa
• AA Sequence: MPPYTVVYFPVRGRCAALRMLLADQ GQSWKEEVVTVETWQEGSLKASCLY GQLPKFQDGDLTLYQSNTIL RHLGRTLGLYGKDQQEAALVDMVND GVEDLRCKYVSLIYTNYEAGKDDYV KALPGQLKPFETLLSQNQGG KTFIVGDQISFADYNLLDLLLIHEV LAPGCLDAFPLLSAYVGRLSARPKL KAFLASPEYVNLPINGNGKQ
  TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Prostate cancer

Gene Information

• Gene Name: GSTP1 glutathione S-transferase pi 1 [ Homo sapiens (human) ]
• Official Symbol: GSTP1
• Synonyms: PI; DFN7; GST3; GSTP; FAEES3; HEL-S-22
• Gene ID: 2950
• mRNA Refseq: NM_000852.4
• Protein Refseq: NP_000843.1
• MIM: 134660
• UniProt ID: P09211