Recombinant Full Length Human HSD17B10 Protein, C-Flag-tagged
Cat.No. : | HSD17B10-341HFL |
Product Overview : | Recombinant Full Length Human HSD17B10 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 25.8 kDa |
AA Sequence : | MAAACRSVKGLVAVITGGASGLGLA TAERLVGQGASAVLLDLPNSGGEAQ AKKLGNNCVFAPADVTSEKD VQTALALAKGKFGRVDVAVNCAGIA VASKTYNLKKGQTHTLEDFQRVLDV NLMGTFNVIRLVAGEMGQNE PDQGGQRGVIINTASVAAFEGQVGQ AAYSASKGGIVGMTLPIARDLAPIG IRVMTIAPGLFGTPLLTSLP EKVCNFLASQVPFPSRLGDPAEYAH LVQAIIENPFLNGEVIRLDGAIRMQ PTRTRPLEQKLISEEDLAANDILDY KDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Alzheimer's disease, Metabolic pathways, Valine, leucine and isoleucine degradation |
Gene Name : | HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 [ Homo sapiens (human) ] |
Official Symbol : | HSD17B10 |
Synonyms : | ABAD; CAMR; ERAB; HCD2; MHBD; HADH2; MRPP2; MRX17; MRX31; SCHAD; MRXS10; SDR5C1; HSD10MD; 17b-HSD10; DUPXp11.22 |
Gene ID : | 3028 |
mRNA Refseq : | NM_004493.3 |
Protein Refseq : | NP_004484.1 |
MIM : | 300256 |
UniProt ID : | Q99714 |
Products Types
◆ Recombinant Protein | ||
HSD17B10-5064H | Recombinant Human HSD17B10 Protein, GST-tagged | +Inquiry |
HSD17B10-2273R | Recombinant Rat HSD17B10 Protein (2-261 aa), His-tagged | +Inquiry |
HSD17B10-1974R | Recombinant Rhesus Macaque HSD17B10 Protein, His (Fc)-Avi-tagged | +Inquiry |
HSD17B10-343C | Recombinant Cynomolgus Monkey HSD17B10 Protein, His (Fc)-Avi-tagged | +Inquiry |
Hsd17b10-1093M | Recombinant Mouse Hsd17b10 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
HSD17B10-5376HCL | Recombinant Human HSD17B10 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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