Recombinant Full Length Human PARVB Protein, C-Flag-tagged

• Cat.No.: PARVB-1249HFL
• Product Overview: Recombinant Full Length Human PARVB Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 41.5 kDa
• AA Sequence: MSSAPRSPTPRPRRMKKDESFLGKL GGTLARKRRAREVSDLQEEGKNAIN SPMSPALADVHPEDTQLEEN EERTMIDPTSKEDPKFKELVKVLLD WINDVLVEERIIVKQLEEDLYDGQV LQKLLEKLAGCKLNVAEVTQ SEIGQKQKLQTVLEAVHDLLRPRGW ALRWSVDSIHGKNLVAILHLLVSLA MHFRAPIRLPEHVTVQVVVV RKREGLLHSSHISEELTTTTEMMMG RFERDAFDTLFDHAPDKLSVVKKSL ITFVNKHLNKLNLEVTELET QFADGVYLVLLMGLLEDYFVPLHHF YLTPESFDQKVHNVSFAFELMLDGG LKKPKARPEDVVNLDLKSTL
  RVLYNLFTKYKNVETRTRPLEQKLI SEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Pathways: Focal adhesion

Gene Information

• Gene Name: PARVB parvin beta [ Homo sapiens (human) ]
• Official Symbol: PARVB
• Synonyms: CGI-56
• Gene ID: 29780
• mRNA Refseq: NM_013327.5
• Protein Refseq: NP_037459.2
• MIM: 608121
• UniProt ID: Q9HBI1