Description : |
This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
41.7 kDa |
AA Sequence : |
MSSAPRSPTPRPRRMKKDESFLGKL GGTLARKRRAREVSDLQEEGKNAIN SPMSPALADVHPEDTQLEENEERTM IDPTSKEDPKFKELVKVLLDWINDV LVEERIIVKQLEEDLYDGQVLQKLL EKLAGCKLNVAEVTQSEIGQKQKLQ TVLEAVHDLLRPRGWALRWSVDSIH GKNLVAILHLLVSLAMHFRAPIRLP EHVTVQVVVVRKREGLLHSSHISEE LTTTTEMMMGRFERDAFDTLFDHAP DKLSVVKKSLITFVNKHLNKLNLEV TELETQFADGVYLVLLMGLLEDYFV PLHHFYLTPESFDQKVHNVSFAFEL MLDGGLKKPKARPEDVVNLDLKSTL RVLYNLFTKYKNVETRTRPLEQKLI SEEDLAANDILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |