Recombinant Full Length Human PCSK1N Protein, C-Flag-tagged

• Cat.No.: PCSK1N-2018HFL
• Product Overview: Recombinant Full Length Human PCSK1N Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene functions as an inhibitor of prohormone convertase 1, which regulates the proteolytic cleavage of neuroendocrine peptide precursors. The proprotein is further processed into multiple short peptides. A polymorphism within this gene may be associated with obesity.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 24 kDa
• AA Sequence: MAGSPLLWGPRAGGVGLLVLLLLGL FRPPPALCARPVKEPRGLSAASPPL AETGAPRRFRRSVPRGEAAG AVQELARALAHLLEAERQERARAEA QEAEDQQARVLAQLLRVWGAPRNSD PALGLDDDPDAPAAQLARAL LRARLDPAALAAQLVPAPVPAAALR PRPPVYDDGPAGPDAEEAGDETPDV DPELLRYLLGRILAGSADSE GVAAPRRLRRAADHDVGSELPPEGV LGALLRVKRLETPAPQVPARRLLPP TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane

Gene Information

• Gene Name: PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor [ Homo sapiens (human) ]
• Official Symbol: PCSK1N
• Synonyms: PEN; SAAS; SCG8; BigLEN; SgVIII; PROSAAS
• Gene ID: 27344
• mRNA Refseq: NM_013271.5
• Protein Refseq: NP_037403.1
• MIM: 300399
• UniProt ID: Q9UHG2