Recombinant Human ABCC2 Protein (M1-F1545), eGFP, Strep II, 10×His tagged
Cat.No. : | ABCC2-0107H |
Product Overview : | Recombinant Human ABCC2(M1-F1545 end)-3C-eGFP-Strep II-10His Protein was expressed in Mammalian cell. |
- Specification
- Gene Information
- Related Products
Description : | ATP-dependent transporter of the ATP-binding cassette (ABC) family that binds and hydrolyzes ATP to enable active transport of various substrates including many drugs, toxicants and endogenous compound across cell membranes. Transports a wide variety of conjugated organic anions such as sulfate-, glucuronide- and glutathione (GSH)-conjugates of endo- and xenobiotics substrates. Mediates hepatobiliary excretion of mono- and bis-glucuronidated bilirubin molecules and therefore play an important role in bilirubin detoxification. Mediates also hepatobiliary excretion of others glucuronide conjugates such as 17beta-estradiol 17-glucosiduronic acid and leukotriene C4. Transports sulfated bile salt such as taurolithocholate sulfate. Transport various anticancer drugs, such as anthracycline, vinca alkaloid and methotrexate and HIV-drugs such as protease inhibitors. Confers resistance to several anti-cancer drugs including cisplatin, doxorubicin, epirubicin, methotrexate, etoposide and vincristine. |
Source : | Mammalian cell |
Species : | Human |
Tag : | eGFP, Strep II,10His |
Form : | Liquid |
Protein Length : | M1-F1545 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 80% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | 50mM Tris-HCl (pH 7.5), 150mM KCl, 2mM DTT, 2mM MgCl2, 0.005% GDN |
Shipping : | It is shipped out with blue ice. |
Gene Name : | ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 [ Homo sapiens (human) ] |
Official Symbol : | ABCC2 |
Synonyms : | ABCC2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; canalicular multispecific organic anion transporter 1, CMOAT; canalicular multispecific organic anion transporter 1; cMRP; DJS; MRP2; canalicular multidrug resistance protein; multidrug resistance-associated protein 2; ATP-binding cassette sub-family C member 2; ABC30; CMOAT; |
Gene ID : | 1244 |
mRNA Refseq : | NM_000392 |
Protein Refseq : | NP_000383 |
MIM : | 601107 |
UniProt ID : | Q92887 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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