| Description : |
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease, a member of the procollagen aminopropeptidase subfamily of proteins, may play a role in the processing of type II fibrillar collagen in articular cartilage. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
135.6 kDa |
| AA Sequence : |
MVLLSLWLIAAALVEVRTSADGQAG NEEMVQIDLPIKRYREYELVTPVST NLEGRYLSHTLSASHKKRSARDVSS NPEQLFFNITAFGKDFHLRLKPNTQ LVAPGAVVEWHETSLVPGNITDPIN NHQPGSATYRIRKTEPLQTNCAYVG DIVDIPGTSVAISNCDGLAGMIKSD NEEYFIEPLERGKQMEEEKGRIHVV YKRSAVEQAPIDMSKDFHYRESDLE GLDDLGTVYGNIHQQLNETMRRRRH AGENDYNIEVLLGVDDSVVRFHGKE HVQNYLLTLMNIVNEIYHDESLGVH INVVLVRMIMLGYAKSISLIERGNP SRSLENVCRWASQQQRSDLNHSEHH DHAIFLTRQDFGPAGMQGYAPVTGM CHPVRSCTLNHEDGFSSAFVVAHET GHVLGMEHDGQGNRCGDETAMGSVM APLVQAAFHRYHWSRCSGQELKRYI HSYDCLLDDPFDHDWPKLPELPGIN YSMDEQCRFDFGVGYKMCTAFRTFD PCKQLWCSHPDNPYFCKTKKGPPLD GTECAAGKWCYKGHCMWKNANQQKQ DGNWGSWTKFGSCSRTCGTGVRFRT RQCNNPMPINGGQDCPGVNFEYQLC NTEECQKHFEDFRAQQCQQRNSHFE YQNTKHHWLPYEHPDPKKRCHLYCQ SKETGDVAYMKQLVHDGTHCSYKDP YSICVRGECVKVGCDKEIGSNKVED KCGVCGGDNSHCRTVKGTFTRTPRK LGYLKMFDIPPGARHVLIQEDEASP HILAIKNQATGHYILNGKGEEAKSR TFIDLGVEWDYNIEDDIESLHTDGP LHDPVIVLIIPQENDTRSSLTYKYI IHEDSVPTINSNNVIQEELDTFEWA LKSWSQCSKPCGGGFQYTKYGCRRK SDNKMVHRSFCEANKKPKPIRRMCN IQECTHPLWVAEEWEHCTKTCGSSG YQLRTVRCLQPLLDGTNRSVHSKYC MGDRPESRRPCNRVPCPAQWKTGPW SECSVTCGEGTEVRQVLCRAGDHCD GEKPESVRACQLPPCNDEPCLGDKS IFCQMEVLARYCSIPGYNKLCCESC SKRSSTLPPPYLLEAAETHDDVISN PSDLPRSLVMPTSLVPYHSETPAKK MSLSSISSVGGPNAYAAFRPNSKPD GANLRQRSAQQAGSKTVRLVTVPSS PPTKRVHLSSASQMAAASFFAASDS IGASSQARTSKKDGKIIDNRRPTRS STLERTRTRPLEQKLISEEDLAAND ILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
