Recombinant Human AGER Protein, His-Flag-StrepII-tagged AGER-421P

Recombinant Human AGER Protein, His-Flag-StrepII-tagged

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Cat.No. : AGER-421P Optional Service: Optional requirements on this protein
Product Overview : Purified AGER (AAH20669.1 23 a.a. - 342 a.a.) human recombinant protein with His-Flag-StrepII tag at N-terminus expressed in human cells.
Description : The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]
Source : HEK293
Species : Human
Tag : His-Flag-StrepII
Form : Liquid
Bio-activity : Not Tested
Molecular Mass : 40.48 kDa
AA Sequence : AQNITARIGE PLVLKCKGAP KKPPQRLEWN LNTGRTEAWK VLSPQGGGPW DSVARVLPNG SLFLPAVGIQ DEGIFRCQAM NRNGKETKSN YRVRVYQIPG KPEIVDSASE LTAGVPNKVG TCVSEGSYPA GTLSWHLDGK PLVPNEKGVS VKEQTRRHPE TGLFTLQSEL MVTPARGGDP RPTFSCSFSP GLPRHRALRT APIQPRVWEP VPLEEVQLVV EPEGGAVAPG GTVTLTCEVP AQPSPQIHWM KDGVPLPLPP SPVLILPEIG PQDQGTYSCV ATHSSHGPQE SRAVSISIIE PGEEGPTAGS VGGSGLGTLA
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80centigrade. Aliquot to avoid repeated freezing and thawing.
Concentration : ≥ 10 ug/ml
Storage Buffer : 100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 5 mM desthiobiotin.
Quality Control Testing: :

Western Blot

SDS-PAGE Gel

Gene Name : AGER advanced glycosylation end product-specific receptor [ Homo sapiens ]
Official Symbol : AGER
Synonyms : AGER; advanced glycosylation end product-specific receptor; RAGE; RAGE isoform sRAGE-delta; RAGE isoform NtRAGE-delta;
Gene ID : 177
mRNA Refseq : NM_001136
Protein Refseq : NP_001127
MIM : 600214
UniProt ID : Q15109
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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