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Recombinant Human AMELY protein, MYC/DDK-tagged

Cat.No. : AMELY-9645H
Product Overview : Recombinant Human AMELY fused with MYC/DDK tag at C-terminal was expressed in HEK293.
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  • Gene Information
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Description : This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in a related gene on chromosome X cause X-linked amelogenesis imperfecta.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 20 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : AMELY amelogenin, Y-linked [ Homo sapiens ]
Official Symbol : AMELY
Synonyms : Amelogenin (Y chromosome); Amelogenin; Amelogenin Y isoform; Amelogenin Y linked; AMELY; AMELY_HUMAN; AMGL; AMGY; Y isoform; AMELY
Gene ID : 266
mRNA Refseq : NM_001143.1
Protein Refseq : NP_001134
MIM : 410000
UniProt ID : Q99218
Chromosome Location : Yp11.2
Function : structural constituent of tooth enamel

Products Types

◆ Recombinant Protein
AMELY-9613H Recombinant Human AMELY, GST-tagged +Inquiry

See All AMELY Recombinant Protein

Related Gene

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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How does AMELY contribute to tooth morphogenesis and differentiation? 08/22/2022

AMELY is involved in tooth morphogenesis and differentiation by regulating the proliferation, differentiation, and mineralization processes during odontogenesis.

How does AMELY expression differ between male and female individuals? 12/12/2021

AMELY expression is specific to male individuals and absent in females.

What are the molecular mechanisms underlying AMELY gene regulation during dental development? 06/01/2021

The regulation of AMELY gene expression during dental development involves intricate interactions between transcription factors, hormonal signals, and genetic cascades.

What are the functional consequences of AMELY mutations or deletions in dental development? 11/04/2020

Mutations or deletions in the AMELY gene can lead to dental abnormalities, specifically affecting male dental development, such as variations in tooth morphology or function.

How does AMELY interact with other dental-specific proteins or signaling pathways? 11/02/2020

AMELY interacts with other dental-specific proteins and signaling pathways, influencing tooth germ development, dental epithelial-mesenchymal interactions, and the formation of male-specific dental structures.

How does AMELY influence odontogenesis processes, such as tooth crown morphology and tissue differentiation? 12/28/2019

AMELY contributes to odontogenesis by influencing tooth crown morphology, establishing tooth shape, size, and structural organization characteristic of male dentition.

Can manipulating AMELY expression or activity provide potential strategies for treating male dental abnormalities or developing gender-specific dental interventions? 07/20/2019

Manipulating AMELY expression or activity holds potential for developing therapeutic strategies targeting male dental abnormalities or gender-specific dental interventions, such as cosmetic dentistry or orthodontic treatments.

What is the role of AMELY in male-specific dental development? 03/29/2019

AMELY plays a crucial role in male-specific dental development, contributing to the formation and differentiation of dental tissues that exhibit sexual dimorphism.

What are the post-translational modifications of AMELY and their significance in dental development? 06/21/2018

AMELY undergoes post-translational modifications, including phosphorylation and glycosylation, which may impact its stability, localization, and interactions with other proteins involved in dental development and differentiation.

How does AMELY impact the molecular pathways involved in tooth mineralization and tissue maturation? 02/14/2018

AMELY influences molecular pathways related to tooth mineralization and tissue maturation, participating in the regulation of dental matrix formation, enamel mineralization, and dentinogenesis processes.

Customer Reviews (3)

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Reviews
01/02/2022

    Enhanced assay sensitivity for detection of subtle protein changes.

    04/19/2019

      Compatibility with complex biological matrices for translational research.

      07/07/2017

        Accurate determination of protein function and activity.

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