Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at IMMUNOLOGY2024™|May 3-7, 2024|Booth #512

Recombinant Human AMPD3 Protein, MYC/DDK-tagged

Cat.No. : AMPD3-1984H
Product Overview : Recombinant human AMPD3 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
  • Specification
  • Gene Information
  • Related Products
  • Download
Description : AMP deaminase plays a critical role in energy metabolism. [UniProtKB/Swiss-Prot Function]
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 89.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : AMPD3 adenosine monophosphate deaminase 3 [ Homo sapiens ]
Official Symbol : AMPD3
Synonyms : AMP aminohydrolase; AMP deaminase 3; adenosine monophosphate deaminase 3; erythrocyte type AMP deaminase; erythrocyte-specific AMP deaminase; myoadenylate deaminase; adenosine monophosphate deaminase (isoform E)
Gene ID : 272
mRNA Refseq : NM_000480.2
Protein Refseq : NP_000471.1
MIM : 102772
UniProt ID : Q01432

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (14)

Ask a question
Are there any ongoing clinical trials targeting AMPD3 protein? 11/21/2022

As of now, there are no known ongoing clinical trials specifically targeting AMPD3 protein. However, it is possible that research is being conducted in this area, and it is always recommended to check clinical trial registries or consult with healthcare professionals for the most up-to-date information on ongoing trials.

Are there any experimental treatments or therapies being explored for AMPD3 protein deficiency? 10/28/2022

Since AMPD3 deficiency is a rare condition with limited understanding, there are no specific experimental treatments or therapies currently being explored. However, as research progresses, there may be potential for the development of targeted therapies in the future. Consulting with healthcare professionals or geneticists who specialize in this area can provide the most up-to-date information on relevant research and potential treatment options.

Where can I find more information about AMPD3 protein deficiency? 07/17/2022

It may be helpful to consult with healthcare professionals or geneticists who specialize in genetic and metabolic disorders for more information about AMPD3 protein deficiency. Additionally, reputable scientific literature, genetics databases, and patient advocacy groups may offer valuable resources on this topic.

What tissues or cell types express AMPD3 protein? 06/02/2022

AMPD3 protein is expressed in various tissues and cell types in the body. It is found in high levels in skeletal muscle, heart muscle, liver, and brain. However, lower levels of expression can also be detected in other tissues, such as kidney, lung, and adipose tissue.

What happens if there is a deficiency of AMPD3 protein? 01/25/2021

A deficiency of AMPD3 protein is associated with an increased risk of certain metabolic disorders and can lead to abnormalities in purine metabolism. However, it is important to note that AMPD3 deficiency is a rare condition and the exact consequences of its deficiency are still being studied.

Are there any genetic variations or mutations associated with AMPD3 protein? 06/03/2020

Yes, there are genetic variations and mutations associated with AMPD3 protein. Single nucleotide polymorphisms (SNPs) have been identified in the AMPD3 gene, which can lead to altered enzyme activity or expression levels. These genetic variations have been linked to certain conditions, such as exercise-induced fatigue or muscle disorders. Additionally, rare mutations in the AMPD3 gene have been found in individuals with a condition called adenosine monophosphate deaminase deficiency, which affects muscle function.

What are the potential therapeutic implications of targeting AMPD3 protein? 04/29/2020

Targeting AMPD3 protein could have therapeutic implications in various diseases or conditions. For instance, since AMPD3 plays a role in purine metabolism, modulating its activity could be beneficial in the treatment of certain forms of cancer, where altered purine metabolism is observed. Inhibiting AMPD3 could potentially limit the production of nucleotides that cancer cells require for their rapid proliferation. On the other hand, the activation of AMPD3 could be explored as a therapeutic approach in neurodegenerative disorders or metabolic diseases, where energy metabolism or cellular stress response is compromised.

Are there any known genetic disorders associated with AMPD3 protein deficiency? 03/25/2020

Currently, there are no known genetic disorders specifically associated with AMPD3 protein deficiency. However, variations in the AMPD3 gene have been identified in some individuals, and further research is needed to understand the potential implications of these variations on health and disease.

How can I conduct research on AMPD3 protein or its related disorders? 01/19/2020

Conducting research on AMPD3 protein or its related disorders typically involves a combination of laboratory experiments, genetic analysis, and literature reviews. If you are a student or researcher, you can access scientific databases, such as PubMed and Scopus, to search for relevant articles and studies. Additionally, consulting with experts in the field, attending scientific conferences, and joining relevant professional societies or research groups may provide further opportunities for research and collaboration.

Are there any known functions or roles of AMPD3 protein beyond purine metabolism? 11/23/2019

While the primary function of AMPD3 protein is related to purine metabolism, recent studies have suggested additional roles for AMPD3. It has been proposed to have functions in energy balance, cellular stress response, and mitochondrial function. However, further research is required to fully unravel the multifaceted functions of AMPD3 protein.

Are there any known inhibitors or activators of AMPD3 protein? 07/27/2018

Currently, there are limited known inhibitors or activators specifically targeting AMPD3 protein. However, there are some compounds that have been shown to modulate AMPD activity in general, which includes AMPD3. For example, certain small molecules, such as PSPC1, have been found to inhibit AMPD activity. Additionally, AMP analogs or activators, such as AICAR (5-aminoimidazole-4-carboxamide ribonucleotide), can activate AMPD enzymes, including AMPD3. Further research is needed to identify more specific and selective inhibitors or activators for AMPD3.

Is there any evidence suggesting a role for AMPD3 protein in aging or longevity? 04/24/2018

While much of the research on AMPD3 protein has focused on its role in metabolism, there is emerging evidence suggesting its involvement in aging or longevity. Studies have shown that AMPD3 expression and activity decline with age, particularly in tissues like skeletal muscle and heart. Additionally, strategies that activate AMPD3, such as caloric restriction or exercise, have been associated with increased lifespan in some organisms. However, more research is needed to fully understand the relationship between AMPD3 and aging.

Can the levels of AMPD3 protein be altered by certain conditions or diseases? 08/11/2016

Yes, the levels of AMPD3 protein can be altered in certain conditions or diseases. For example, exercise or physical activity has been shown to increase the expression of AMPD3 in skeletal muscle. On the other hand, some studies have reported associations between alterations in AMPD3 expression and conditions such as cancer, cardiovascular disease, and neurodegenerative disorders. However, more research is needed to fully understand the implications of these associations.

Is the expression of AMPD3 protein regulated in any way? 05/03/2016

Yes, the expression of AMPD3 protein is regulated. It can be influenced by various factors, including transcriptional and post-transcriptional mechanisms. For example, certain signaling pathways and transcription factors can regulate the expression of the AMPD3 gene. Additionally, microRNAs or other non-coding RNAs can interact with the messenger RNA (mRNA) of AMPD3 and affect its translation into protein.

Customer Reviews (5)

Write a review
Reviews
07/01/2022

    Its utilization in this technique has allowed for precise visualization and determination of protein structures with remarkable clarity and resolution.

    05/18/2021

      Its excellent performance in this application makes it a valuable asset in immunoassays and other biochemical studies.

      02/16/2019

        Ampd3 protein has exhibited remarkable performance in Western Blotting experiments.

        03/02/2018

          Ampd3 protein has proved to be an invaluable tool in protein electron microscopy structure analysis.

          08/05/2017

            The reliable and high-quality results obtained using Ampd3 protein make it an excellent choice for researchers studying protein structures.

            Ask a Question for All AMPD3 Products

            Required fields are marked with *

            My Review for All AMPD3 Products

            Required fields are marked with *

            0

            Inquiry Basket

            cartIcon
            logo

            FOLLOW US

            Terms and Conditions        Privacy Policy

            Copyright © 2024 Creative BioMart. All Rights Reserved.

            Contact Us

            • /

            Stay Updated on the Latest Bioscience Trends