Recombinant Human ANXA8, His-tagged

• Cat.No.: ANXA8-27322TH
• Product Overview: Recombinant full length Human Annexin VIII with an N terminal His tag; 347 amino acids with tag, MWt 39kDa.

Specification

• Description: This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.
• Protein length: 327 amino acids
• Conjugation: HIS
• Molecular Weight: 39.000kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM EDTA, 1mM DTT, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMAWWK SWIEQEGVTVKSSSHFNPDPDAETL YKAMKGIGTNEQAIIDVLTKRSNTQ RQQIAKSFKAQFGKDLTETLKSELS GKFERLIVALMYPPYRYEAKELHDA MKGLGTKEGVIIEILASRTKNQLRE IMKAYEEDYGSSLEEDIQADTSGYL ERILVCLLQGSRDDVSSFVDPGLAL QDAQDLYAAGEKIRGTDEMKFITIL CTRSATHLLRVFEEYEKIANKSIED SIKSETHGSLEEAMLTVVKCTQNLH SYFAERLYYAMKGAGTRDGTLIRNI VSRSEIDLNLIKCHFKKMYGKTLSS MIMEDTSGDYKNALLSLVGSDP
• Sequence Similarities: Belongs to the annexin family.Contains 4 annexin repeats.

Gene Information

• Gene Name: ANXA8 annexin A8 [ Homo sapiens ]
• Official Symbol: ANXA8
• Synonyms: ANXA8; annexin A8; ANX8
• Gene ID: 653145
• mRNA Refseq: NM_001040084
• Protein Refseq: NP_001035173
• MIM: 602396
• Uniprot ID: P13928
• Chromosome Location: 10q11.22
• Function: calcium ion binding; calcium-dependent phospholipid binding