Recombinant Human BCL2A1 Protein

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Recombinant Human BCL2A1 Protein

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Cat.No. : BCL2A1-862H
Product Overview : Recombinant Human BCL2A1(Met1-Ser152), transcript variant 2, was expressed in E. coli.
Description : This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source : E. coli
Species : Human
Form : 20mM Phosphate buffer, 150mM NaCl, 1mM EDTA, 1mM DTT, 10% Glycerol, pH 7.4. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Molecular Mass : 18.5 kDa
Endotoxin : < 0.1 EU per µg protein as determined by LAL test
Purity : >95% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : BCL2A1 BCL2-related protein A1 [ Homo sapiens ]
Official Symbol : BCL2A1
Synonyms : BCL2A1; BCL2-related protein A1; HBPA1; bcl-2-related protein A1; ACC 1; ACC 2; BCL2L5; BFL1; GRS; bcl2-L-5; protein BFL-1; bcl-2-like protein 5; hematopoietic BCL2-related protein A1; hemopoietic-specific early response protein; ACC-1; ACC-2;
Gene ID : 597
mRNA Refseq : NM_001114735
Protein Refseq : NP_001108207
MIM : 601056
UniProt ID : Q16548
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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