Cat.No. :	CA12-805H
Product Overview :	Recombinant Human Carbonic Anhydrase XII, Variant 2 was expressed in Sf9 insect cells.
Description :	Carbonic anhydrases (CAs) are enzymes which catalyze the reversible hydration of carbon dioxide according to the following reaction: CO2 + H2O ↔ HCO3- + H+. The main function of this protein family is to regulate the acid-base balance, which is of a considerable biological importance. In addition, they participate in several other physiological functions including CO2 and HCO3- transport, bone resorption, production of biological fluids, ureagenesis, gluconeogenesis and lipogenesis. Carbonic anhydrases are metalloenzymes containing a zinc-atom in their active site. The expanding CA gene family includes at least 13 enzymatically active members with different structural and catalytic properties. His-tag removed.
Source :	Insect cell
Species :	Human
Form :	50 mM Tris-HCl pH 7.5 and 0.05 M NaN3, pH 7.5
Molecular Mass :	30 kDa
AASequence :	GS (residues remained after His-tag removal) APVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ
Purity :	> 95 % (SDS-PAGE under reducing conditions)
Storage :	Store at -80 centigrade, avoid freeze/thaw cycles.

Gene Name :	CA12 carbonic anhydrase XII [ Homo sapiens ]
Official Symbol :	CA12
Synonyms :	CAXII; CA-XII; T18816; HsT18816
Gene ID :	771
mRNA Refseq :	NM_001218.4
Protein Refseq :	NP_001209.1
MIM :	603263
UniProt ID :	O43570

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