Recombinant Human CA12 Protein

• Cat.No.: CA12-805H
• Product Overview: Recombinant Human Carbonic Anhydrase XII, Variant 2 was expressed in Sf9 insect cells.

Specification

• Description: Carbonic anhydrases (CAs) are enzymes which catalyze the reversible hydration of carbon dioxide according to the following reaction: CO2 + H2O ↔ HCO3- + H+. The main function of this protein family is to regulate the acid-base balance, which is of a considerable biological importance. In addition, they participate in several other physiological functions including CO2 and HCO3- transport, bone resorption, production of biological fluids, ureagenesis, gluconeogenesis and lipogenesis. Carbonic anhydrases are metalloenzymes containing a zinc-atom in their active site. The expanding CA gene family includes at least 13 enzymatically active members with different structural and catalytic properties. His-tag removed.
• Source: Insect cell
• Species: Human
• Form: 50 mM Tris-HCl pH 7.5 and 0.05 M NaN3, pH 7.5
• Molecular Mass: 30 kDa
• AASequence: GS (residues remained after His-tag removal) APVNGSKWTYFGPDGENSWSKKYPS CGGLLQSPIDLHSDILQYDASLTPL EFQGYNLSANKQFLLTNNGHSVKLN LPSDMHIQGLQSRYSATQLHLHWGN PNDPHGSEHTVSGQHFAAELHIVHY NSDLYPDASTASNKSEGLAVLAVLI EMGSFNPSYDKIFSHLQHVKYKGQE AFVPGFNIEELLPERTAEYYRYRGS LTTPPCNPTVLWTVFRNPVQISQEQ LLALETALYCTHMDDPSPREMINNF RQVQKFDERLVYTSFSQ
• Purity: > 95 % (SDS-PAGE under reducing conditions)
• Storage: Store at -80 centigrade, avoid freeze/thaw cycles.

Gene Information

• Gene Name: CA12 carbonic anhydrase XII [ Homo sapiens ]
• Official Symbol: CA12
• Synonyms: CAXII; CA-XII; T18816; HsT18816
• Gene ID: 771
• mRNA Refseq: NM_001218.4
• Protein Refseq: NP_001209.1
• MIM: 603263
• UniProt ID: O43570