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Recombinant Human CCL5 protein, MYC/DDK-tagged

Cat.No. : CCL5-82H
Product Overview : Recombinant Human CCL5 fused with MYC/DDK tag at C-terminal was expressed in HEK293.
  • Specification
  • Gene Information
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Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 7.8 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Notes : Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Concentration : > 50 ug/mL as determined by microplate BCA method
Gene Name : CCL5 chemokine (C-C motif) ligand 5 [ Homo sapiens ]
Official Symbol : CCL5
Synonyms : CCL5; chemokine (C-C motif) ligand 5; D17S136E, SCYA5, small inducible cytokine A5 (RANTES); C-C motif chemokine 5; beta chemokine RANTES; MGC17164; RANTES; regulated upon activation; normally T expressed; and presumably secreted; SIS delta; SISd; small inducible cytokine subfamily A (Cys Cys); member 5; T cell specific protein p288; T cell specific RANTES protein; TCP228; eoCP; SIS-delta; beta-chemokine RANTES; small-inducible cytokine A5; T-cell specific protein p288; t cell-specific protein P228; T-cell-specific protein RANTES; eosinophil chemotactic cytokine; small inducible cytokine A5 (RANTES); small inducible cytokine subfamily A (Cys-Cys), member 5; regulated upon activation, normally T-expressed, and presumably secreted; SCYA5; D17S136E;
Gene ID : 6352
mRNA Refseq : NM_002985
Protein Refseq : NP_002976
MIM : 187011
UniProt ID : P13501
Chromosome Location : 17q11.2-q12
Pathway : Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem;
Function : CCR1 chemokine receptor binding; CCR1 chemokine receptor binding; CCR1 chemokine receptor binding; CCR4 chemokine receptor binding; CCR5 chemokine receptor binding; chemoattractant activity; chemokine activity; chemokine activity; chemokine receptor antagonist activity; chemokine receptor binding; heparin binding; phosphatidylinositol phospholipase C activity; phospholipase activator activity; protein homodimerization activity; protein kinase activity; protein self-association; receptor signaling protein tyrosine kinase activator activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What are the potential clinical applications of CCL5 inhibitors? 10/24/2021

CCL5 inhibitors may be used to control inflammation in diseases like rheumatoid arthritis or as an adjuvant in cancer therapy.

Can CCL5 be used to stimulate the immune system in cancer treatment? 10/24/2020

CCL5-based immunotherapies are being explored to enhance the immune response against cancer cells.

Can CCL5 be used as a diagnostic marker for diseases? 08/14/2019

It can serve as a biomarker for some diseases, but it is usually used in conjunction with other markers for more accurate diagnostics.

What are the clinical implications of elevated CCL5 levels? 02/20/2019

Elevated CCL5 levels are associated with inflammation and may be indicative of certain diseases such as rheumatoid arthritis or HIV infection.

Are there any CCL5-targeted therapies in development? 05/18/2018

Yes, there are ongoing efforts to develop therapies that modulate CCL5 activity, particularly in diseases involving inflammation.

Customer Reviews (3)

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Reviews
08/17/2021

    This specificity enables precise quantification and characterization of CCL5 and its interactions with other molecules or proteins of interest.

    06/23/2019

      Its exceptional performance, coupled with its ability to generate clear and precise protein bands, make it an indispensable tool in achieving accurate and reliable results.

      06/20/2016

        The CCL5 protein exhibits a high degree of specificity in various assays, ensuring accurate and reliable results.

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