CCL5 Protein


Home / Products / CCL5


Official Full Name chemokine (C-C motif) ligand 5
Background This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
Synonyms CCL5; chemokine (C-C motif) ligand 5; SISd; eoCP; SCYA5; RANTES; TCP228; D17S136E; SIS-delta; C-C motif chemokine 5; beta-chemokine RANTES; T-cell specific protein p288; eosinophil chemotactic cytokine; small inducible cytokine subfamily A (Cys-Cys), member 5; regulated upon activation, normally T-expressed, and presumably secreted;
    • Species :
    • Bovine
    • Cattle
    • Chicken
    • Cotton Rat
    • Cynomolgus Monkey
    • Dog
    • Guinea pig
    • Horse
    • Human
    • Mouse
    • Mouse/Rat
    • Pig
    • Rabbit
    • Rat
    • Rhesus
    • Rhesus Macaque
    • Rhesus monkey
    • Swine
    • Source :
    • CHO
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Human Cells
    • In Vitro Cell Free System
    • Mamanlian cells
    • Mammalian Cell
    • Mammalian cells
    • Mouse
    • Wheat Germ
    • Yeast
    • Tag :
    • Biotin
    • Fc
    • Flag
    • GST
    • His
    • His & mucin
    • S
    • T7
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    • N-His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CCL5-114H Active Human CCL5 N/A Inquiry
    Human CCL5-510H Active Recombinant Mouse Chemokine (C-C motif) Ligand 5, MIgG2a Fc-tagged CHO Fc Inquiry
    Human CCL5-511H Active Recombinant Mouse Chemokine (C-C motif) Ligand 5, HIgG1 Fc-tagged, mutant CHO Fc Inquiry
    Human CCL5-512H Active Recombinant Mouse Chemokine (C-C motif) Ligand 5, HIgG1 Fc-tagged CHO Fc Inquiry
    Human CCL5-81H Active Recombinant Human CCL5 protein HEK293 N/A Inquiry
    Mouse Ccl5-259M Active Recombinant Mouse Chemokine (C-C motif) Ligand 5 Mouse N/A Inquiry
    Cotton Rat Ccl5-385C Active Recombinant Cotton Rat Ccl5 E.coli N/A Inquiry
    Rat Ccl5-104R Recombinant Rat Chemokine (C-C Motif) Ligand 5 E.coli N/A Inquiry
    Human CCL5-0642H Recombinant Human CCL5 Protein, GST-Tagged Wheat Germ GST Inquiry
    Human CCL5-125H Recombinant Human Chemokine (C-C Motif) Ligand 5 Mammalian cells N/A Inquiry
    Human CCL5-301H Recombinant Human CCL5 protein E.coli N/A Inquiry
    Human CCL5-61H Recombinant Human chemokine (C-C motif) ligand 5, His-tagged E.coli His Inquiry
    Human CCL5-773H Recombinant Human CCL5 protein, His & T7-tagged E.coli His/T7 Inquiry
    Human CCL5-82H Recombinant Human CCL5 protein, MYC/DDK-tagged HEK293 Myc/DDK Inquiry
    Human CCL5-85H Recombinant Human CCL5, His tagged Human Cell His Inquiry
    Mouse CCL5-2977M Recombinant Mouse CCL5 Protein Mammalian Cell His Inquiry
    Mouse Ccl5-616M Recombinant Mouse Ccl5 protein E.coli N/A Inquiry
    Mouse Ccl5-774M Recombinant Mouse Ccl5 protein, His & GST-tagged E.coli His/GST Inquiry
    Rhesus Macaque CCL5-693R Recombinant Rhesus monkey CCL5 Protein, His-tagged Mammalian Cell His Inquiry
    Rhesus monkey CCL5-776R Recombinant Rhesus monkey CCL5 protein, His-tagged E.coli His Inquiry
    Dog CCL5-770D Recombinant Dog CCL5 protein, His & S-tagged E.coli His/S Inquiry
    Bovine CCL5-132B Recombinant Bovine Chemokine (C-C motif) Ligand 5 Yeast N/A Inquiry
    Chicken CCL5-3492C Recombinant Chicken CCL5 Mammalian Cell His Inquiry
    Pig CCL5-147S Recombinant Swine Chemokine (C-C motif) Ligand 5 Yeast N/A Inquiry
    Pig CCL5-22S Recombinant Swine CCL5 Yeast N/A Inquiry
    Horse CCL5-771H Recombinant Horse CCL5 protein, His & T7-tagged E.coli His/T7 Inquiry
    Guinea pig Ccl5-772G Recombinant Guinea pig Ccl5 protein, His & GST-tagged E.coli His/GST Inquiry
    Pig CCL5-775P Recombinant Pig CCL5 protein, His & T7-tagged E.coli His/T7 Inquiry
    Human CCL5-2706HCL Recombinant Human CCL5 cell lysate Human Cell N/A Inquiry
    Human CCL5-302H Recombinant Human CCL5 protein, His-tagged E.coli His Inquiry
    Human CCL5-059C Recombinant Human CCL5 Protein (68 aa) E.coli Inquiry
    Human CCL5-1068HFL Recombinant Full Length Human CCL5 Protein, C-Flag-tagged Mammalian cells Flag Inquiry
    Cattle CCL5-1206C Recombinant Cattle CCL5 Protein, His-tagged E.coli N-His Inquiry
    Human CCL5-151H Recombinant Human CCL5 Protein, His-tagged Human Cells His Inquiry
    Human CCL5-165C Recombinant Human CCL5 Protein (68 aa) HEK293 Inquiry
    Human CCL5-27H Recombinant Human CCL5 Protein E.coli Inquiry
    Mouse/Rat Ccl5-28M Recombinant Mouse/Rat CCL5 Protein E.coli Inquiry
    Human CCL5-2954HF Recombinant Full Length Human CCL5 Protein, GST-tagged In Vitro Cell Free System GST Inquiry
    Mouse/Rat Ccl5-29M Recombinant Mouse/Rat CCL5 Protein E.coli Inquiry
    Mouse/Rat Ccl5-30M Recombinant Mouse/Rat CCL5 Protein E.coli Inquiry
    Human CCL5-352H Recombinant Human CCL5 Protein, His & mucin-tagged HEK293 His & mucin Inquiry
    Human CCL5-3993HFL Recombinant Full Length Human CCL5 protein, Flag-tagged Mamanlian cells Flag Inquiry
    Human CCL5-43H Recombinant Human CCL5 Protein E.coli Inquiry
    Human CCL5-57H Recombinant Human CCL5 Protein, Biotin-tagged E.coli Biotin Inquiry
    Human CCL5-120H Human Rantes (rDNA derived) Reference standard N/A Inquiry
    Human CCL5-2625H Recombinant Human CCL5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK Inquiry
    Human CCL5-513HG GMP Recombinant Human CCL5 protein, Fc-tagged HEK293 Fc Inquiry
    Mouse Ccl5-133M Recombinant Mouse Ccl5 Protein E.coli Inquiry
    Mouse Ccl5-2039M Recombinant Mouse Ccl5 Protein E. coli Inquiry
    Mouse Ccl5-2040M Recombinant Mouse Ccl5 Protein, Myc/DDK-tagged HEK293T Myc/DDK Inquiry
    Rat CCL5-312R Recombinant Rat CCL5 Protein, His-tagged Yeast His Inquiry
    Cynomolgus Monkey CCL5-4397C Recombinant Cynomolgus Monkey CCL5 Protein Yeast N/A Inquiry
    Rhesus CCL5-3411R Recombinant Rhesus CCL5 protein E.coli N/A Inquiry
    Rabbit CCL5-4353R Recombinant Rabbit CCL5 Protein Yeast N/A Inquiry
    Swine CCL5-4354S Recombinant Swine CCL5 Protein Yeast N/A Inquiry

    CCL5 involved in several pathways and played different roles in them. We selected most pathways CCL5 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, Toll-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction CXCL13; NGFRB; CCL18; TNFRSF8; HGF; CNTFR; CCL25; TNFRSF13C; CCR5; KITLG
    Chemokine signaling pathway RAP1A; Ccl27a; AMCF-II; PRKACB; GNB4; RAF1; GNB1; LOC100033925; CCL5; STAT5B
    Toll-like receptor signaling pathway MAPK13; IL8L1; MAPK8B; MAP2K4A; IRAK1; TMED7-TICAM2; IRAK4; MAPK9; CRFB2; AKT2L
    NOD-like receptor signaling pathway PYCARD; NFKBIAA; MAPK14B; NLRP3; CASP1; NFKBIB; MAPK8A; MAP3K7IP3; CXCL1; BIRC2
    Cytosolic DNA-sensing pathway IRF7; IFNA1; RIPK1; IFNA6; IFNA2; NFKBIB; NFKBIAA; IFNA5; IFNB1; CASPA
    TNF signaling pathway CREB3L3; CASP8; CCL2; PIK3CG; MMP3; CX3CL1; IL15; CXCL3; TNFRSF1B; IKBKB
    Prion diseases C8A; IL6; LAMC1; MAP2K2; PRKACG; MAPK1; C6; BAX; MAPK3; LOC100033925
    Epithelial cell signaling in Helicobacter pylori infection ATP6V1C1; RELA; LYN; GIT1; F11R; ATP6V0A1; ATP6V1D; MAPK11; ADAM17; CXCL1
    Chagas disease (American trypanosomiasis) AKT2; MAPK10; GNA11; TLR9; NFKBIA; ACE; IL6; CD3G; GNAI3; GNAO1
    Influenza A IFNA1; MAPK9; FAS; HSPA1L; MAPK13; PRSS3; IFNGR1; TLR3; IL18; MAP2K7
    Herpes simplex infection PTPN11; IFNG1-2; IFNG; NFKB1; CCL2; IFNA21; C5; IRF7; Hc; FADD
    Rheumatoid arthritis CCL5; IL6; IFNG; HLA-DRB3; TNF; ATP6V1C2; ATP6V1B1; ATP6V0D1; TNFSF13B; ATP6V0E1

    CCL5 has several biochemical functions, for example, CCR1 chemokine receptor binding, CCR4 chemokine receptor binding, CCR5 chemokine receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL5 itself. We selected most functions CCL5 had, and list some proteins which have the same functions with CCL5. You can find most of the proteins on our site.

    Function Related Protein
    CCR1 chemokine receptor binding CCL4; CCL7; CCL3; CCL23; CCL5; CREB3
    CCR4 chemokine receptor binding CCL5
    CCR5 chemokine receptor binding CCL3; JAK1; CCL5; CCL4; CNIH4; STAT3
    chemoattractant activity LGALS3; BMP4; VEGFB; CCL16; CXCL12; VEGFC; HGF; FGF7; CXCL12B; SAA4
    chemokine activity CCL25B; PF4; XCL1; CXCL2; Ccl21a; CXCL3; IL-8; CCL21; CCL38A.4; Ccl21c
    chemokine receptor antagonist activity CCL5
    chemokine receptor binding Ccl21c; CCRL2; CXCL12; CCL21B; S100A14; CCL5; Ccl21a; CCL25; CCL21; CCL19
    heparin binding SERPINA10; LAMC2; WISP1B; SLIT1A; NELL2; PGF; THBS1; PCOLCE2; COL20A1; KNG1
    phosphatidylinositol phospholipase C activity PLCB4; PLCD3; PLCE1; CCR1; PLD4; CHRM5; PLCG1; CCKBR; PLCL2; C3AR1
    phospholipase activator activity APOC2; PDPK1; CCL8; ARHGAP6; CCL5; CCL3; GM2A
    protein binding IL5; BLMH; GOLSYN; FCGR1A; WLS; GAGE8; FMNL1; ZNF207; Unc5b; HSFY1
    protein homodimerization activity PLOD1; DROSHA; LGALS6; Anks6; OLIG2; CD2; NR4A3; PAH; FASN; COMMD1
    protein kinase activity BUB1B; COL4A3BP; AURKA; PRKAG1; EGFRA; CAMKK1B; PKN1; GRK7B; RIPK3; RPS6KA5
    protein self-association TMEM190; SVIP; CCDC88C; ACHE; CNTN2; SLC9A3R1; VAMP2; AGA; MDH2; RYR2
    receptor signaling protein tyrosine kinase activator activity CCL5

    CCL5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL5 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL5.


    Yin, Q; Fan, Q; et al. Spinal NF-kappa B and Chemokine Ligand 5 Expression during Spinal Glial Cell Activation in a Neuropathic Pain Model. PLOS ONE 10:-(2015).
    Ricciardi, A; Dalton, JP; et al. Evaluation of the immune response and protective efficacy of Schistosoma mansoni Cathepsin B in mice using CpG dinucleotides as adjuvant. VACCINE 33:346-353(2015).

    Q&As (0)

    Ask a Question for All CCL5 Products

    Required fields are marked with *

    • Verification Code

    Related Services & Products

    Apply For A Coupon

    $50 OFF Your First Purchase

    Apply For a Coupon

    Enter your email here to subscribe.

    creative biomart inc.

    Easy access to products and services you need from our library via powerful searching tools.

    Follow Us

    Copyright © 2023 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy