Active Recombinant Human CD22 protein, His-Avi-tagged, Biotinylated
Cat.No. : | CD22-273HB |
Product Overview : | Biotinylated Recombinant Human CD22 protein(Asp 20 - Arg 687), fused with His and Avi tag, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | His-Avi |
Form : | Lyophilized from 0.22 μm filtered solution in 20 mM MES, 150 mM NaCl, pH5.5, 10% trehalose. |
Bio-activity : | Immobilized Biotinylated Human Siglec-2, His,Avitag at 1 μg/mL (100 μL/well) on streptavidin precoated (0.5 μg/well) plate can bind Monoclonal Anti-Human Siglec-2 Antibody, Human IgG1 with a linear range of 1-10 ng/mL. |
Molecular Mass : | This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).The protein has a calculated MW of 78.7 kDa. The protein migrates as 100-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein Length : | Asp 20 - Arg 687 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. >90% as determined by SEC-MALS. |
Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | CD22 CD22 molecule [ Homo sapiens ] |
Official Symbol : | CD22 |
Synonyms : | CD22; CD22 molecule; CD22 antigen; B-cell receptor CD22; sialic acid binding Ig like lectin 2; SIGLEC 2; SIGLEC2; BL-CAM; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; SIGLEC-2; FLJ22814; MGC130020; |
Gene ID : | 933 |
mRNA Refseq : | NM_001185099 |
Protein Refseq : | NP_001172028 |
MIM : | 107266 |
UniProt ID : | P20273 |
Products Types
◆ Lysates | ||
CD22-001MCL | Recombinant Mouse CD22 cell lysate | +Inquiry |
CD22-1956HCL | Recombinant Human CD22 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCD22-targeted immunotherapy is more targeted, specifically attacking cancer cells, whereas chemotherapy affects both healthy and cancerous cells.
Yes, CD22-targeted therapies are often used in combination with chemotherapy or other immunotherapies for enhanced efficacy.
CD22-targeted therapies are being explored for autoimmune diseases like rheumatoid arthritis and systemic lupus erythematosus.
Yes, CD22 is targeted in immunotherapy for B cell malignancies like acute lymphoblastic leukemia (ALL).
CD22 acts as an inhibitory receptor, regulating B cell activation and signaling.
Customer Reviews (3)
Write a reviewThe CD22 protein offers numerous advantages in trials and research studies, making it an excellent choice for scientists in need of reliable and high-quality experimental materials.
Its unique properties make CD22 an invaluable tool for investigating cellular signaling pathways, protein-protein interactions, and membrane dynamics.
With the CD22 protein and its accompanying technical assistance, I am confident that I can achieve successful outcomes for my research endeavors.
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