| Official Full Name | CD22 molecule |
| Background | CD22 or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins.[1] It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases. |
| Synonyms | SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; BLCAM; Leu14; Siglec-2; Bectumomab; LymphoScan; 158318-63-9; Epratuzumab; 205923-57-5; Moxetumomab pasudotox; 1020748-57-5; Inotuzumab ozogamicin; 635715-01-4 |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
cd22 involved in several pathways and played different roles in them. We selected most pathways cd22 participated on our site, such as Cell adhesion molecules (CAMs), Hematopoietic cell lineage, B cell receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with cd22 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell adhesion molecules (CAMs) | CLDN15A; Ntng2; LRRC4C; JAM3B; CLDN15; PTPRM; MPZL1L; HLA-DRB3; GLYCAM1; MHC1UEA |
| Hematopoietic cell lineage | EPOR; CD1D; ITGA5; Flt3l; IL1R1; CD24; IL11RA2; CD5; HLA-DRB1; IL1B |
| B cell receptor signaling pathway | LYN; NFKBIE; DOK3; PLEKHA1; PIK3R5; MALT1; CDK2; VAV3; GRB2; PPP3R2 |
cd22 has several biochemical functions, for example, carbohydrate binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cd22 itself. We selected most functions cd22 had, and list some proteins which have the same functions with cd22. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbohydrate binding | LGALS2; GALNT14; LGALS9; Siglece; REG3B; DGCR2; KLRC1; GCKR; Pla2r1; VCAN |
| protein binding | COMMD3; GNL3L; HTRA3; OIP5; SPEF2; MAP3K7; LGALS6; TDGF1; VPS28; A1CF |
cd22 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cd22 here. Most of them are supplied by our site. Hope this information will be useful for your research of cd22.
SYK; LYN; PLCG1; PTPN6; PTPRC; cpxA; PIK3R1
