Cat.No. :	CD40LG-0816H
Product Overview :	Purified CD40LG (AAH74950.1, 116 a.a. - 261 a.a.) human recombinant protein with His-Flag-StrepII tag at N-terminus expressed in human cells.
Description :	The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]
Source :	Human cells
Species :	Human
Tag :	His-Flag-StrepII
Form :	Liquid
Bio-activity :	Not Tested
Molecular Mass :	21.34 kDa
AA Sequence :	GDQNPQIAAHVISEASSKTTSVLQWAEKGYYTMSNNLVTLENGKQLTVKRQGLYYIYAQVTFCSNREASSQAPFIASLCLKSPGRFERILLRAANTHSSAKPCGQQSIHLGGVFELQPGASVFVNVTDPSQVSHGTGFTSFGLLKL
Applications :	Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array
Storage :	Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Concentration :	≥ 10 μg/mL
Storage Buffer :	100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 5 mM desthiobiotin.
Quality Control Testing :	SDS-PAGE Gel Western Blot

Gene Name :	CD40LG CD40 ligand [ Homo sapiens ]
Official Symbol :	CD40LG
Synonyms :	CD40LG; CD40 ligand; HIGM1, IMD3, TNFSF5, tumor necrosis factor (ligand) superfamily, member 5 (hyper IgM syndrome); CD40 antigen ligand; CD40L; CD154; gp39; hCD40L; hyper IgM syndrome; T B cell activating molecule; TNF related activation protein; TRAP; tumor necrosis factor (ligand) superfamily member 5; CD40-L; T-cell antigen Gp39; T-B cell-activating molecule; TNF-related activation protein; IGM; IMD3; HIGM1; T-BAM; TNFSF5;
Gene ID :	959
mRNA Refseq :	NM_000074
Protein Refseq :	NP_000065
MIM :	300386
UniProt ID :	P29965

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