cd40lg

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cd40lg

Official Full Name CD40 ligand
Background The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
Synonyms CD40LG; CD40 ligand; IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L; CD40-L; CD40 antigen ligand; T-cell antigen Gp39; T-B cell-activating molecule; TNF-related activation protein; tumor necrosis factor (ligand) superfamily member 5; tu
    • Species :
    • Canine
    • Cattle
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Human/Rhesus macaque
    • Mouse
    • Pig
    • Rabbit
    • Rat
    • Rhesus Macaque
    • Rhesus monkey
    • Zebrafish
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • Avi
    • Fc
    • Flag
    • GST
    • His
    • StrepII
    • S
    • human
    • IgG1
    • Mouse
    • IgG2a
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CD40LG-280H Recombinant Human CD40LG Protein, Fc-Avi-tagged, Biotinylated HEK293 Avi/Fc
    Human/Rhesus macaque CD40LG-324H Recombinant Human/Rhesus macaque CD40LG protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc
    Mouse CD40LG-325M Recombinant Mouse CD40LG protein, His-tagged HEK293 His
    Rabbit CD40LG-392R Recombinant Rabbit CD40LG Protein (113-261 aa), His-tagged E.coli His
    Human CD40LG-019E Recombinant Human CD40LG (108-261aa) E.coli N/A
    Human CD40LG-0815H Recombinant Human CD40LG Protein Wheat Germ N/A
    Human CD40LG-0816H Recombinant Human CD40LG Protein, His-Flag-StrepII-Tagged Human Cell His/Flag/StrepII
    Human CD40LG-0818H Recombinant Human CD40LG Protein, GST-Tagged Wheat Germ GST
    Human CD40LG-117H Recombinant Human CD40LG protein, His-tagged HEK293 His
    Human CD40LG-156HG GMP Recombinant Human CD40LG Protein HEK293 N/A
    Human CD40LG-193H Recombinant Human CD40LG, FLAG-tagged CHO Flag
    Human CD40LG-1965HCL Recombinant Human CD40LG cell lysate Human Cell N/A
    Human CD40LG-22H Recombinant Human Soluble CD40 Ligand E.coli N/A
    Human CD40LG-23H Recombinant Human CD40LG E.coli N/A
    Human CD40LG-26080TH Recombinant Human CD40LG protein E.coli N/A
    Human CD40LG-27811TH Recombinant Human CD40LG, His-tagged E.coli His
    Human CD40LG-279H Recombinant Human CD40LG protein, Fc-tagged HEK293 human/IgG1/Fc
    Human CD40LG-33H Recombinant Human CD40LG, HIgG1 Fc-tagged CHO Fc
    Human CD40LG-34H Recombinant Human CD40LG, MIgG2a Fc-tagged CHO Fc
    Human CD40LG-4349HG GMP Recombinant Human CD40LG protein E.coli N/A
    Human CD40LG-4737H Recombinant Human CD40 Ligand E.coli N/A
    Human CD40LG-783H Recombinant Human CD40LG protein, His & S-tagged E.coli His/S
    Human CD40LG-784H Recombinant Human CD40LG protein, His-tagged E.coli His
    Human CD40LG-785H Recombinant Human CD40LG protein, His & GST-tagged E.coli His/GST
    Mouse CD40LG-1548MCL Recombinant Mouse CD40LG cell lysate Human Cell N/A
    Mouse Cd40lg-404M Recombinant Mouse Cd40lg, FLAG-tagged CHO Flag
    Mouse Cd40lg-4371M Recombinant Mouse Cd40lg Protein Yeast N/A
    Mouse Cd40lg-43M Recombinant Mouse Cd40lg protein, Fc-tagged HEK293 human/IgG1/Fc
    Mouse Cd40lg-786M Recombinant Mouse Cd40lg protein, His & GST-tagged E.coli His/GST
    Mouse CD40lg-83M Recombinant Mouse CD40lg protein, His-tagged Insect Cell His
    Mouse Cd40lg-98M Recombinant Mouse CD40 Ligand E.coli N/A
    Rat CD40LG-1205RCL Recombinant Rat CD40LG cell lysate Human Cell N/A
    Rat CD40LG-1253R Recombinant Rat CD40LG Protein Mammalian Cell His
    Rat Cd40lg-405R Recombinant Rat Cd40lg, FLAG-tagged CHO Flag
    Rat Cd40lg-545R Recombinant Rat Cd40lg, Fc tagged Human Cell Fc
    Rat Cd40lg-790R Recombinant Rat Cd40lg protein, His & GST-tagged E.coli His/GST
    Rat Cd40lg-8725R Recombinant Rat Cd40lg, Fc-tagged Human Cell Fc
    Cynomolgus Monkey CD40LG-1080CCL Recombinant Cynomolgus CD40LG cell lysate Human Cell N/A
    Cynomolgus Monkey CD40LG-69C Recombinant Cynomolgus CD40LG, Fc tagged Human Cell Fc
    Rhesus Macaque CD40LG-741R Recombinant Rhesus monkey CD40LG Protein, His-tagged Mammalian Cell His
    Rhesus monkey CD40LG-791R Recombinant Rhesus monkey CD40LG protein, His-tagged E.coli His
    Canine CD40LG-001CCL Recombinant Canine CD40LG cell lysate Human Cell N/A
    Canine CD40LG-107C Recombinant Canine CD40LG Yeast N/A
    Canine CD40LG-166C Recombinant Canine CD40LG Human Cell N/A
    Canine CD40LG-167C Recombinant Canine CD40LG, Fc-tagged Human Cell Fc
    Chicken CD40LG-108C Recombinant Chicken CD40LG Yeast N/A
    Rabbit CD40LG-25R Recombinant Rabbit CD40LG Protein, His-tagged Yeast His
    Chicken CD40LG-6298C Recombinant Chicken CD40LG Mammalian Cell His
    Zebrafish CD40LG-7294Z Recombinant Zebrafish CD40LG Mammalian Cell His
    Pig CD40LG-102S Recombinant Swine CD40LG Yeast N/A
    Cattle CD40LG-782C Recombinant Cattle CD40LG protein, His & GST-tagged E.coli His/GST
    Pig CD40LG-787P Recombinant Pig CD40LG protein, His & S-tagged E.coli His/S
    Pig CD40LG-788P Recombinant Pig CD40LG protein, His-tagged E.coli His
    Pig CD40LG-789P Recombinant Pig CD40LG protein, His & GST-tagged E.coli His/GST

    cd40lg involved in several pathways and played different roles in them. We selected most pathways cd40lg participated on our site, such as Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with cd40lg were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction TNFRSF12A; IL24; CCL15; IL20RB; CCL25; IFNAR1; LEPA; IFNA3; CCL3; IL12BA
    NF-kappa B signaling pathway TNF; MAP3K7; RIPK1; SYK; CXCL2; BIRC3; TNFAIP3; MAP3K7IP3; GM1987; TNFSF11
    Cell adhesion molecules (CAMs) PRPSAP2; ITGB2L; NRXN2A; ITGB1A; HLA-DPA1; SDC3; H2-Q10; NLGN2B; CD8A; CLDND
    T cell receptor signaling pathway MAP2K1; NFATC2; NFKBIA; PPP3R1; PPP3CB; ZAP70; CD8B; CD8A; NFATC3; MAP3K7
    Intestinal i ICOS; BMA1; HLA-DRB3; IL4; H2-AB1; CD40LG; CCL27B; BLB2; MHC2A; IL6
    ne network for IgA production MHC2A; CD28; CCL27B; MHC2DAB; TGFB1A; CCL25B; HLA-DQB1; CD40; CCL28; MHC2DCB
    Malaria MET; SDC2; TNF; PECAM1; TGFB3; LRP1; KLRB1; THBS4; HBB-B2; THBS2
    Toxoplasmosis MAP2K6; HSPA1B; TGFB3; BCL2L1; Toxoplasma Gondii Major Surface Antigen P30; BIRC3; IL12B; TAB2; NFKBIA; GNAI2
    Asthma HLA-DOA; HLA-DRB3; IL13; IL9; CD40; H2-AA; HLA-DQA1; HLA-DRB5; RNASE3; FCER1G
    Autoi HLA-DPB1; GZMB; CD28; IFNA8; IFNA17; IFNA10; HLA-DPA1; HLA-E; IL4; Ifna11
    ne thyroid disease HLA-DPB1; HLA-DOA; Ifna11; HLA-B; CD28; HLA-F; HLA-E; HLA-A; IFNA8; Ifna15
    Systemic lupus erythematosus HIST2H2BB; ACTN2; C8A; HIST1H3H; C2; SSB; HLA-DMB; HIST1H3A; HIST1H2BC; H2AFZ
    Allograft rejection Il2; HLA-DPA1; TNF; Fasl; H2-AA; IL12B; MICA; HLA-DMA; CD28; GZMB
    Primary i IGLL1; IL2RG; AIRE; CD40; UNG; CD3E; RFXAP; CD8A; RFX5; DCLRE1C
    nodeficiency IGLL1; RAG2; ICOS; TNFRSF13B; RAG1; UNG; PTPRC; RFXAP; CD4; CD8B1
    Viral myocarditis HLA-DPA1; HLA-DRB5; BID; SGCG; HLA-DQA1; CAV1; HLA-F; H2-AB1; CXADR; CD40LG

    cd40lg has several biochemical functions, for example, CD40 receptor binding, cytokine activity, tumor necrosis factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cd40lg itself. We selected most functions cd40lg had, and list some proteins which have the same functions with cd40lg. You can find most of the proteins on our site.

    Function Related Protein
    CD40 receptor binding CD40LG; TRAF2
    cytokine activity BMP7B; SECTM1; TNFSF9; IFNL3; IL6; IL13; Flt3l; CCL20A.3; IL3; IFNA3
    tumor necrosis factor receptor binding TNFSF11; TNFSF10; Fasl; CD40LG; CD70; LTB; TNFSF14; TNF; TRAF1; TRAF2

    cd40lg has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cd40lg here. Most of them are supplied by our site. Hope this information will be useful for your research of cd40lg.

    Britze, A; Palmfeldt, J; et al. 44-plex cytokine profile of cholesteatoma. ACTA OTO-LARYNGOLOGICA 134:41-50(2014).
    Strickland, FM; Hewagama, A; et al. Diet Influences Expression of Autoimmune-Associated Genes and Disease Severity by Epigenetic Mechanisms in a Transgenic Mouse Model of Lupus. ARTHRITIS AND RHEUMATISM 65:1872-1881(2013).

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