Recombinant Human CLEC4M, Fc tagged

• Cat.No.: CLEC4M-3132H
• Product Overview: Recombinant Human CLEC4M extracellular domain (Ser 78-Glu 399) (NP_055072.3), fused with the Fc region of human IgG1 at the N-terminus, was produced in Human Cell.

Specification

• Source: Human Cells
• Species: Human
• Tag: Fc
• Form: Lyophilized from sterile PBS, pH 7.4
• Molecular Mass: The recombinant human DC-SIGNR/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 580 amino acids and has a predicted molecular mass of 65 kDa. As a result of glycosylation, the apparent molecular mass of rhDC-SIGNR/Fc is approximately 110-140 kDa & 65-70 kDa corresponding to the homodimer and monomer respectively in SDS-PAGE under non-reduced conditions.
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Stability: Samples are stable for up to twelve months from date of receipt at -70oC.
• Storage: Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: CLEC4M C-type lectin domain family 4, member M [ Homo sapiens ]
• Official Symbol: CLEC4M
• Gene ID: 10332
• mRNA Refseq: NM_001144904
• Protein Refseq: NP_001138376
• MIM: 605872
• UniProt ID: Q9H2X3

Reviews

04/13/2021

Its outstanding performance, coupled with its ease of use, has enhanced the overall efficiency and accuracy of my research.

07/28/2018

I highly recommend the CLEC4M Protein to researchers seeking a reliable and high-performing protein for their ELISA assays and protein electron microscopy structure analysis.

07/04/2018

The CLEC4M Protein has greatly contributed to the success of my experiments, providing reliable and robust data.

Q&As

Are there any diseases or conditions associated with CLEC4M dysfunction?

Research suggests that CLEC4M may be involved in the pathogenesis of certain viral infections, as well as in modulating immune responses in conditions such as HIV and hepatitis.

What are the potential clinical applications of CLEC4M in the context of viral infections?

CLEC4M could potentially be targeted for the development of antiviral therapies or vaccines, as its role in recognizing and responding to viral pathogens is of great interest to researchers.

What are the implications of CLEC4M in the field of vaccine development?

CLEC4M's role in recognizing viral pathogens makes it an interesting target for vaccine development, as it may be involved in eliciting immune responses against specific viruses.

How does CLEC4M contribute to the immune response in the context of fungal infections?

CLEC4M has been shown to recognize and bind to specific carbohydrates present on the surface of certain fungi, contributing to immune responses against fungal pathogens.

How does CLEC4M function in the context of viral infections?

CLEC4M binds to viral glycoproteins, facilitating the uptake of viruses into dendritic cells and promoting antiviral immune responses.